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GlossaryMethotrexate (Trexall)

inhibits cell growth by blocking folic acid metabolism

Methotrexate (MTX) is a medication commonly used to treat certain types of cancer, autoimmune diseases like rheumatoid arthritis, and severe psoriasis. It works by inhibiting the metabolism of folic acid, which is necessary for the rapid growth of cells, thereby slowing down the proliferation of cancer cells and modulating the immune system.

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Tofacitinib for the Treatment of Three Immune-Mediated Conditions in One Patient: Ulcerative Colitis, Pyoderma Gangrenosum, and Alopecia Areata

research Tofacitinib for the Treatment of Three Immune-Mediated Conditions in One Patient: Ulcerative Colitis, Pyoderma Gangrenosum, and Alopecia Areata

5 citations , January 2021 in “Inflammatory Bowel Diseases”

Tofacitinib improved ulcerative colitis, skin ulcers, and hair loss in a patient who didn't respond well to other treatments.

research Treatment Modalities for Lymphocytic and Neutrophilic Scarring Alopecia

August 2023 in “Journal of The American Academy of Dermatology”

Early treatment is key for permanent hair loss disorders, with options ranging from medications and phototherapy to immunomodulators and antibiotics, depending on severity and type.

research Autoimmune Polyglandular Syndrome Type 4 – Case Report

January 2019 in “Przegląd Dermatologiczny”

Patients with one autoimmune disease should be checked for other autoimmune disorders.

research Safety of Common Medications for Treating Dermatology Disorders in Pregnant Women

7 citations , September 2013 in “Current Dermatology Reports”

Some skin medications are safe for pregnant women, but others pose risks or should not be used.

research Lupus Erythematosus: Considerations About Clinical, Cutaneous, and Therapeutic Aspects

15 citations , January 2014 in “Anais Brasileiros de Dermatologia”

Lupus treatment requires a combination of drugs and therapies, with research needed for new options.

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