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GlossaryMetastatic Melanoma

advanced skin cancer spread to other body parts

Metastatic melanoma, also known as Stage IV melanoma, is an advanced form of skin cancer where the melanoma cells have spread from the original tumor site to other parts of the body, such as the lungs, liver, brain, or bones. This stage of melanoma is particularly challenging to treat and often requires a combination of therapies, including surgery, immunotherapy, targeted therapy, and radiation.

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research Hair and Nail Adverse Events During Treatment with Targeted Therapies for Metastatic Melanoma

April 2016 in “Journal of The American Academy of Dermatology”

People with certain allergic conditions or higher white blood cell counts have more severe hair loss, and treating hair and nail side effects early in melanoma therapy can improve quality of life.

research Metastatic Melanoma of the Tongue: A Rare Case

November 2012 in “Actas Dermo-Sifiliográficas”

An 86-year-old man had a rare tongue melanoma but refused treatment, showing the need for early cancer detection and treatment.

research Resolution of Paraneoplastic Alopecia Areata Following Nivolumab in a Patient With Metastatic Melanoma

1 citations, June 2023 in “JAAD case reports”

Nivolumab treatment led to hair regrowth in a man with metastatic melanoma and alopecia areata.

research Hair and Nail Adverse Events During Treatment with Targeted Therapies for Metastatic Melanoma

32 citations, May 2016 in “European journal of dermatology/EJD. European journal of dermatology”

Targeted therapies for advanced skin cancer often cause hair and nail problems, which need managing to avoid changing the treatment dose.

The Cutaneous Side Effects of Selective BRAF Inhibitors and Anti-CTLA4 Agents: The Growing Role of the Dermatologist in the Management of Patients with Metastatic Melanoma

research The Cutaneous Side Effects of Selective BRAF Inhibitors and Anti-CTLA4 Agents: The Growing Role of the Dermatologist in the Management of Patients with Metastatic Melanoma

6 citations, April 2013 in “Current Dermatology Reports”

Dermatologists are crucial for managing skin side effects in metastatic melanoma patients using vemurafenib and ipilimumab.

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community Ketoconazole mesotherapy plausible?

in Ketoconazole 9 upvotes 6 months ago

The conversation discusses using ketoconazole, an anti-androgen, for hair loss and whether mesotherapy with dermarolling could enhance its absorption into the scalp. The user questions if the typical 2% ketoconazole shampoo dose would be effective when used after dermarolling to target androgen receptors in the scalp.

community Can finasteride affect on your muscle and other things?

in Finasteride/Dutasteride 1 upvotes 1 year ago

The conversation discusses using finasteride topically for hair loss and concerns about potential side effects like feminization and impact on muscle growth. One person shared their experience with finasteride, indicating it increased testosterone and did not prevent them from gaining muscle or strength.

community Dermatologist told me to quit fin after turning 40

in Finasteride/Dutasteride 194 upvotes 1 year ago

A dermatologist advised a patient to stop taking finasteride (fin) after turning 40 due to potential risk of aggressive prostate cancer. The patient and others in the conversation debated this advice, discussing the relationship between finasteride, prostate cancer, and hair loss, and considering alternatives like topical finasteride.

community Prolactin’s role in antitumor activity of the immune system – a safety concern for HMI-115?

in Research/Science 3 upvotes 1 year ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Prolactin's role in immune system's antitumor activity raises safety concerns for HMI-115.