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    Glossary Melanomas

    Melanomas are a type of skin cancer that arises from melanocytes, the cells responsible for producing the pigment melanin, which gives color to the skin, hair, and eyes. While primarily associated with skin lesions, melanomas can also affect hair follicles and lead to changes in hair pigmentation or hair loss in the affected areas. Their relevance to hair loss lies in the potential for aggressive growth and metastasis, which can impact overall health and lead to complications that may include hair loss. Key distinguishing characteristics of melanomas include asymmetrical shapes, irregular borders, varied colors, and a diameter larger than 6mm.

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    1. The Three-Dimensional Human Skin Reconstruct Model: a Tool to Study Normal Skin and Melanoma Progression Journal of Visualized Experiments · 2011 · 110 citations
    2. Development of Heritable Melanoma in Transgenic Mice Journal of Investigative Dermatology · 1998 · 75 citations
    3. A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease Nature Communications · 2019 · 67 citations
    4. Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution and Tumor Initiating Cells Medical Sciences · 2017 · 37 citations
    5. Anatomic location of primary melanoma: Survival differences and sun exposure Journal of The American Academy of Dermatology · 2019 · 27 citations
    6. AMPK Phosphorylates ZDHHC13 to Increase MC1R Activity and Suppress Melanomagenesis Cancer Research · 2023 · 24 citations
    7. Sun-protection behaviors of melanoma survivors Journal of The American Academy of Dermatology · 2011 · 24 citations
    8. Dysplastic nevi, cutaneous melanoma, and other skin neoplasms in patients with myotonic dystrophy type 1: A cross-sectional study Journal of The American Academy of Dermatology · 2015 · 23 citations
    9. N-(3,5-Dimethylphenyl)-3-Methoxybenzamide (A3B5) Targets TRP-2 and Inhibits Melanogenesis and Melanoma Growth 2011 · 15 citations
    10. Essential Role for Integrin-Linked Kinase in Melanoblast Colonization of the Skin Journal of Investigative Dermatology · 2019 · 14 citations
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