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    Glossary Melanomas

    Melanomas are a type of skin cancer that arises from melanocytes, the cells responsible for producing the pigment melanin, which gives color to the skin, hair, and eyes. While primarily associated with skin lesions, melanomas can also affect hair follicles and lead to changes in hair pigmentation or hair loss in the affected areas. Their relevance to hair loss lies in the potential for aggressive growth and metastasis, which can impact overall health and lead to complications that may include hair loss. Key distinguishing characteristics of melanomas include asymmetrical shapes, irregular borders, varied colors, and a diameter larger than 6mm.

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    1. The Three-Dimensional Human Skin Reconstruct Model: a Tool to Study Normal Skin and Melanoma Progression Journal of Visualized Experiments · 2011 · 110 citations
    2. Development of Heritable Melanoma in Transgenic Mice Journal of Investigative Dermatology · 1998 · 75 citations
    3. A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease Nature Communications · 2019 · 67 citations
    4. Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution and Tumor Initiating Cells Medical Sciences · 2017 · 37 citations
    5. Anatomic location of primary melanoma: Survival differences and sun exposure Journal of The American Academy of Dermatology · 2019 · 27 citations
    6. AMPK Phosphorylates ZDHHC13 to Increase MC1R Activity and Suppress Melanomagenesis Cancer Research · 2023 · 24 citations
    7. Sun-protection behaviors of melanoma survivors Journal of The American Academy of Dermatology · 2011 · 24 citations
    8. Dysplastic nevi, cutaneous melanoma, and other skin neoplasms in patients with myotonic dystrophy type 1: A cross-sectional study Journal of The American Academy of Dermatology · 2015 · 23 citations
    9. N-(3,5-Dimethylphenyl)-3-Methoxybenzamide (A3B5) Targets TRP-2 and Inhibits Melanogenesis and Melanoma Growth 2011 · 15 citations
    10. Essential Role for Integrin-Linked Kinase in Melanoblast Colonization of the Skin Journal of Investigative Dermatology · 2019 · 14 citations
    11. Loss of ‘Epidermal Melanin Unit’ Integrity in Human Skin During Melanoma-Genesis Frontiers in oncology · 2022 · 13 citations
    12. Carvone Decreases Melanin Content by Inhibiting Melanoma Cell Proliferation via the Cyclic Adenosine Monophosphate (cAMP) Pathway Molecules · 2020 · 12 citations
    13. Malignant Melanoma and Its Stromal Nonimmune Microecosystem Journal of Oncology · 2012 · 10 citations
    14. Nestin is expressed in HMB‐45 negative melanoma cells in dermal parts of nodular melanoma The Journal of Dermatology · 2010 · 9 citations
    15. Hair(y) Matters in Melanoma Biology Trends in molecular medicine · 2020 · 7 citations
    16. Topical Application of Thymidine Dinucleotide to Newborn Mice Reduces and Delays Development of UV-Induced Melanomas 2012 · 5 citations
    17. Nano-pulse stimulation™ therapy (NPS™) is superior to cryoablation in clearing murine melanoma tumors Frontiers in Oncology · 2023 · 4 citations
    18. An exclusive review of melatonin effects on mammalian melanocytes and melanoma Experimental dermatology · 2022 · 3 citations
    19. Left-sided excess of melanoma occurrence but not of other skin cancers: Additional evidence Journal of the American Academy of Dermatology · 2011 · 2 citations
    20. Lentiginous melanoma. A clinically malignant entity that histopathologically seems benign. Case study harbouring BRAF V 600R mutation Journal of the European Academy of Dermatology and Venereology · 2015 · 1 citations
    21. Sentinel lymph node status is the strongest independent predictor for disease free and overall survival in patients with thick melanoma Journal of the European Academy of Dermatology and Venereology · 2012 · 1 citations
    22. Metastasis of an Untreated Thin Melanoma in a Very Elderly Patient International Journal of Dermatology · 1990 · 1 citations
    23. A Melanoma Transplanted in Nude Mice Has Both Host‐ and Tumor‐Derived Blood Vessel‐ and Nerve‐Like Structures Cancer Science · 2026
    24. Clinical, Dermoscopic, and Histological Characteristics of Melanoma Patients According to the Age Groups: A Retrospective Observational Study Life · 2023
    25. 1272 p21Waf1/Cip1 is differentially expressed in epidermal versus follicular melanocytes and melanoma cells and is phenotypically regulated by UVB-mediated apoptosis 2023
    26. 202 Automated assessment of tumor infiltrating lymphocytes informs mortality in thin melanoma Journal of Investigative Dermatology · 2023
    27. Author response: Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma 2021
    28. Predictors of sentinel lymph node metastasis in melanoma Yearbook of Dermatology and Dermatologic Surgery · 2011
    29. Is knowledge about the genetic and epigenetic alterations in melanoma a basis for targeted therapy? Experimental Dermatology · 2006
    30. Silk‐Inspired In Situ Hydrogel with Anti‐Tumor Immunity Enhanced Photodynamic Therapy for Melanoma and Infected Wound Healing Advanced Functional Materials · 2021 · 59 citations