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Glossary Prostate Cancer Cells

abnormal cells originating in the prostate gland, potentially spreading

Prostate cancer cells are abnormal cells that originate in the prostate gland, a small gland in men that produces seminal fluid. These cells can grow uncontrollably and form tumors, potentially spreading to other parts of the body (metastasis). Also known as prostate carcinoma cells, they are the focus of various diagnostic and treatment strategies in oncology.

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Research

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research Matriptase activation and shedding with HAI-1 is induced by steroid sex hormones in human prostate cancer cells, but not in breast cancer cells

56 citations , February 2006 in “American journal of physiology. Cell physiology”

This study observed that in hormone-starved prostate cancer cells, the androgen 5alpha-dihydrotestosterone rapidly induces matriptase activation and shedding, which involves androgen receptor signaling and requires both transcription and protein synthesis.

research High-throughput and direct measurement of androgen levels using turbulent flow chromatography liquid chromatography-triple quadrupole mass spectrometry (TFC-LC-TQMS) to discover chemicals that modulate dihydrotestosterone production in human prostate cancer cells

2 citations , November 2017 in “Biotechnology Letters”

This study developed a high-throughput method that identifies bioactive chemicals influencing DHT production in prostate cancer cells, with potential nutraceutical candidates including fucoxanthin, phenethyl caffeate, and Curcuma longa L. extract.

research Possible association between androgenic alopecia and risk of prostate cancer and testicular germ cell tumor: a systematic review and meta-analysis

3 citations , March 2018 in “BMC Cancer”

This study found that androgenic alopecia was associated with a decreased risk of testicular germ cell tumors but a potential increased risk of high-grade prostate cancer.

research Additional file 4: of Possible association between androgenic alopecia and risk of prostate cancer and testicular germ cell tumor: a systematic review and meta-analysis

January 2018 in “Figshare”

There might be a link between male pattern baldness and a higher risk of prostate cancer and testicular cancer.

research 411 THE POTENTIAL OF CIRCULATING ENDOTHELIAL CELLS AS PROGNOSTIC BIOMARKERS IN PROSTATE CANCER

March 2011 in “European Urology Supplements”

CEC levels may be a useful marker for predicting prostate cancer progression.

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Community Join

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community Research: Minoxidil grows hair by suppressing androgen activity (DHT) in hair follicles.

43 upvotes 6 years ago

Minoxidil may suppress androgen activity in hair follicles, potentially aiding in hair growth and prostate cancer treatment. Users discuss the effectiveness of minoxidil and finasteride for hair maintenance and regrowth, with some preferring topical applications over oral due to safety concerns.

community Dermatologist told me to quit fin after turning 40

in Finasteride/Dutasteride 194 upvotes 2 years ago

A dermatologist advised a patient to stop taking finasteride (fin) after turning 40 due to potential risk of aggressive prostate cancer. The patient and others in the conversation debated this advice, discussing the relationship between finasteride, prostate cancer, and hair loss, and considering alternatives like topical finasteride.

community Expectations control for SCUBE3

20 upvotes 2 years ago

SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

community "Hair Follicle Stem Cells are quiescent 99% of the time and permanently reside in the hair follicle"

in Research/Science 1391 upvotes 1 year ago

Hair follicles are mostly dormant but can be reactivated with treatments like minoxidil, finasteride, and microneedling. A new drug, PP405, shows promise for hair regrowth but may not be available until 2027-2028.

community Did anybody use beta sisterol for hair loss? I saw in many articles in the internet that said that beta sisterol blocks dht by inhibiting 5a reductase type 2 enzyme and some reviews of people who said that it worked better than saw palmetto in terms of stoping hair loss and helping prostate.

in Research/Science 9 upvotes 3 years ago

Beta-sitosterol may inhibit 5-alpha reductase type 2 enzyme, potentially reducing DHT levels and promoting hair growth, similar to finasteride but possibly with fewer side effects. Its effectiveness and side effects compared to other treatments like saw palmetto and finasteride remain uncertain due to limited research.

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Learn

4 / 800 results

learn Bicalutamide

Nonsteroidal anti-androgen, originally a prostate cancer drug

learn Baicapil

Does Baicapil block DHT? What the evidence shows No published study shows that Baicapil blocks DHT — the only data on the ingredient itself is the manufacturer's own unpublished dossier, and the baicalin research behind the claim is prostate cancer cell-line work that did not measure DHT or hair.

learn Mesotherapy

Injections of drug or vitamin mixtures into the scalp

learn Cyproterone

Is cyproterone only for women, or can men use it too? Cyproterone acetate is not a women-only drug — published reports describe use in men for prostate cancer, paraphilic disorders and gender-affirming therapy — but it is not FDA-approved for any indication, and European regulators restricted higher doses over a dose-related meningioma risk.

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