High-Throughput and Direct Measurement of Androgen Levels Using Turbulent Flow Chromatography Liquid Chromatography-Triple Quadrupole Mass Spectrometry to Discover Chemicals That Modulate Dihydrotestosterone Production in Human Prostate Cancer Cells
November 2017
in “
Biotechnology Letters
”
androgen levels turbulent flow chromatography liquid chromatography triple quadrupole mass spectrometry TFC-LC-TQMS testosterone dihydrotestosterone DHT prostate cancer cells phytochemicals fucoxanthin phenethyl caffeate Curcuma longa L. extract naringenin androgen-modulatory nutraceuticals Curcuma longa L. turmeric
Studysummary This study developed a high-throughput method that identifies bioactive chemicals influencing DHT production in prostate cancer cells, with potential nutraceutical candidates including fucoxanthin, phenethyl caffeate, and Curcuma longa L. extract.
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