Loss of Epidermal Melanin Unit Integrity in Human Skin During Melanoma Genesis

    April 2022 in “ Frontiers in oncology ”
    Cristina Casalou, Hugo Moreiras, Jay M. Mayatra … Desmond J. Tobin
    Studysummary This review discusses the early phases of melanomagenesis and the factors influencing melanoma cell variability and reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 9

    1. A Novel Mouse Model Demonstrates That Oncogenic Melanocyte Stem Cells Engender Melanoma Resembling Human Disease Nature Communications · 2019
    2. Hair Follicle Regeneration Suppresses Ras-Driven Oncogenic Growth Journal of Cell Biology · 2019
    3. From Neural Crest Cells to Melanocytes: Cellular Plasticity During Development and Beyond Cellular and Molecular Life Sciences · 2019
    4. Cancer Risk in Patients with Alopecia Areata: A Nationwide Population-Based Matched Cohort Study Cancer Medicine · 2018
    5. Resting No More: Redefining Telogen, the Maintenance Stage of the Hair Growth Cycle Biological Reviews · 2014
    6. Melanocyte Stem Cells: A Melanocyte Reservoir in Hair Follicles for Hair and Skin Pigmentation Pigment Cell & Melanoma Research · 2011
    7. The Cell Biology of Human Hair Follicle Pigmentation Pigment cell & melanoma research · 2010
    8. Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    9. Do Hair Bulb Melanocytes Undergo Apoptosis During Hair Follicle Regression (Catagen)? ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998

    Related research 3

    1. Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle PloS one · 2015
    2. Functionally Distinct Melanocyte Populations Revealed by Reconstitution of Hair Follicles in Mice Pigment Cell & Melanoma Research · 2010
    3. The Silver Locus Product (Silv/gp100/Pmel17) as a New Tool for the Analysis of Melanosome Transfer in Human Melanocyte–Keratinocyte Co-Culture Experimental dermatology · 2008