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Glossary Melanocyte

cell producing melanin, pigment for skin, hair, eyes

A melanocyte is a type of cell found in the skin, eyes, and hair follicles that produces melanin, the pigment responsible for the color of your skin, hair, and eyes. These cells play a crucial role in protecting the skin from harmful UV radiation by absorbing and dissipating it. In conditions like vitiligo or certain types of alopecia, the function or presence of melanocytes can be disrupted, leading to changes in pigmentation.

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research Skin melanocytes: biology and development

401 citations , January 2013 in “Postepy Dermatologii I Alergologii”

This review discusses the biology and development of skin melanocytes, but reports no new clinical findings.

research Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells

283 citations , February 2011 in “Cell stem cell”

COL17A1 is crucial for preventing hair graying and loss by supporting hair and pigment stem cells.

research Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells

260 citations , January 2020 in “Nature”

Stress can cause hair to turn gray by depleting stem cells.

research Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration

260 citations , June 2011 in “Cell”

This study found that Wnt signaling in the hair follicle is crucial for coordinating the behavior of epithelial and melanocyte stem cells, which drives hair regeneration and melanocyte differentiation in mice.

research Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation

240 citations , April 2011 in “Pigment Cell & Melanoma Research”

This review discusses the identification and characteristics of melanocyte stem cells, emphasizing their role in hair pigmentation, greying, and skin repigmentation, but reports no new research findings.

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