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    Glossary Melanocyte

    cell producing melanin, pigment for skin, hair, eyes

    A melanocyte is a type of cell found in the skin, eyes, and hair follicles that produces melanin, the pigment responsible for the color of your skin, hair, and eyes. These cells play a crucial role in protecting the skin from harmful UV radiation by absorbing and dissipating it. In conditions like vitiligo or certain types of alopecia, the function or presence of melanocytes can be disrupted, leading to changes in pigmentation.

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    1. Skin melanocytes: biology and development Postepy Dermatologii I Alergologii · 2013 · 401 citations
    2. Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells Cell stem cell · 2011 · 283 citations
    3. Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells Nature · 2020 · 260 citations
    4. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011 · 260 citations
    5. Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation Pigment Cell & Melanoma Research · 2011 · 240 citations
    6. Towards a “free radical theory of graying”: melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage ˜The œFASEB journal · 2006 · 210 citations
    7. Melanogenesis is coupled to murine anagen: Toward new concepts for the role of melanocytes and the regulation of melanogenesis in hair growth 1993 · 210 citations
    8. Long-term follow-up of leucoderma patients treated with transplants of autologous cultured melanocytes, ultrathin epidermal sheets and basal cell layer suspension 2002 · 177 citations
    9. Human dermal stem cells differentiate into functional epidermal melanocytes Journal of Cell Science · 2010 · 164 citations
    10. The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling ˜The œAmerican journal of pathology · 2002 · 146 citations
    11. Do Hair Bulb Melanocytes Undergo Apotosis During Hair Follicle Regression (Catagen)? 1998 · 130 citations
    12. Melanogenesis Is Coupled to Murine Anagen: Toward New Concepts for the Role of Melanocytes and the Regulation of Melanogenesis in Hair Growth. 1993 · 109 citations
    13. Melanocyte Stem Cell Maintenance and Hair Graying Cell · 2005 · 105 citations
    14. Melanocytes: The new Black The International Journal of Biochemistry & Cell Biology · 2006 · 93 citations
    15. Human Epidermal Neural Crest Stem Cells (hEPI-NCSC)—Characterization and Directed Differentiation into Osteocytes and Melanocytes Stem Cell Reviews and Reports · 2011 · 91 citations
    16. Melanocyte Subpopulation Turnover During the Human Hair Cycle: An Immunohistochemical Study Pigment cell research · 2000 · 86 citations
    17. Molecular Regulation of Melanocyte Senescence Pigment Cell Research · 2002 · 85 citations
    18. Structure and function of melanocytes: microscopic morphology and cell biology of mouse melanocytes in the epidermis and hair follicle. PubMed · 1995 · 69 citations
    19. The silver locus product (Silv/gp100/Pmel17) as a new tool for the analysis of melanosome transfer in human melanocyte–keratinocyte co‐culture Experimental dermatology · 2008 · 68 citations
    20. A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease Nature Communications · 2019 · 67 citations
    21. From neural crest cells to melanocytes: cellular plasticity during development and beyond Cellular and Molecular Life Sciences · 2019 · 66 citations
    22. Direct conversion of mouse and human fibroblasts to functional melanocytes by defined factors Nature Communications · 2014 · 66 citations
    23. EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling Cell Reports · 2016 · 59 citations
    24. The chemokine SDF-1/CXCL12 regulates the migration of melanocyte progenitors in mouse hair follicles Differentiation · 2009 · 57 citations
    25. Electron Microscope Studies of the Human Epidermis The Clear Cell of Masson (Dendritic Cell or Melanocyte) The Journal of Cell Biology · 1958 · 56 citations
    26. Keratinocytes regulate the function of melanocytes 2014 · 55 citations
    27. Premature Graying as a Consequence of Compromised Antioxidant Activity in Hair Bulb Melanocytes and Their Precursors PLOS ONE · 2014 · 46 citations
    28. Wnt/β-catenin signaling pathway activates melanocyte stem cells in vitro and in vivo Journal of Dermatological Science · 2016 · 45 citations
    29. Hair melanocytes as neuro-endocrine sensors—Pigments for our imagination Molecular and cellular endocrinology · 2005 · 43 citations
    30. CD34 defines melanocyte stem cell subpopulations with distinct regenerative properties PLOS genetics · 2019 · 41 citations