Androgen Action in the Ovary
August 2018
in “
Frontiers in Endocrinology
”
androgens estradiol follicle development granulosa cell proliferation preantral follicles antral follicles apoptosis mono-follicular ovulation androgen signaling genomic effects non-genomic effects polycystic ovary syndrome PCOS intra-ovarian androgen excess epigenetic modifications follicle atresia FSH deficiency FSH
Studysummary This review discusses the physiological roles of ovarian androgens in follicle development and atresia, emphasizing their contributions to polycystic ovary syndrome and normal follicle maturation but provides no new clinical results.
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