In Search of New Therapeutics: Molecular Aspects of the PCOS Pathophysiology - Genetics, Hormones, Metabolism and Beyond

    September 2020 in “ International Journal of Molecular Sciences ”
    Agata Wawrzkiewicz-Jałowiecka, Karolina Kowalczyk, Paulina Trybek … Paweł Madej
    Studysummary This review discusses the disruption of hormonal and metabolic rhythms in polycystic ovary syndrome and explores potential drug targets to address its molecular causes, without providing new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on mdpi.com →
    Discuss this study in the Community →

    Research cited in this study 18

    1. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    2. The Efficacy and Use of Finasteride in Women: A Systematic Review International Journal of Dermatology · 2019
    3. Polycystic Ovary Syndrome: Overview and Management Nursing Clinics of North America · 2018
    4. Kisspeptin and LH Pulsatile Temporal Coupling in PCOS Patients Endocrine · 2018
    5. Anxiety, Depression, and Quality of Life in Women with Polycystic Ovarian Syndrome Indian Journal of Psychological Medicine · 2018
    6. Polycystic Ovary Syndrome (PCOS): An Inflammatory, Systemic, Lifestyle Endocrinopathy Journal of steroid biochemistry and molecular biology/˜The œJournal of steroid biochemistry and molecular biology · 2018
    7. Sex Hormone-Binding Globulin: An Important Biomarker for Predicting PCOS Risk - A Systematic Review and Meta-Analysis Systems Biology in Reproductive Medicine · 2017
    8. The Role of Aquaporins in Polycystic Ovary Syndrome: A Way Towards a Novel Drug Target in PCOS Medical Hypotheses · 2017
    9. The Prevalence and Phenotypic Features of Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis Human Reproduction · 2016
    10. Genetic, Hormonal, and Metabolic Aspects of PCOS: An Update Reproductive Biology and Endocrinology · 2016
    11. Polycystic Ovary Syndrome: Insight Into Pathogenesis and a Common Association With Insulin Resistance Clinical Medicine · 2016
    12. Anti-Müllerian Hormone Gene Polymorphism Is Associated With Androgen Levels in Chinese Polycystic Ovary Syndrome Patients With Insulin Resistance Journal of Assisted Reproduction and Genetics · 2016
    13. Polycystic Ovary Syndrome: Insight Into Pathogenesis and a Common Association With Insulin Resistance Clinical Medicine · 2015
    14. Intermittent Low-Dose Finasteride Administration Is Effective for Treatment of Hirsutism in Adolescent Girls: A Pilot Study Journal of Pediatric and Adolescent Gynecology · 2014
    15. A Randomized, Placebo-Controlled Trial of 1% Topical Minoxidil Solution in the Treatment of Androgenetic Alopecia in Japanese Women PubMed · 2007
    16. Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline The Journal of Clinical Endocrinology and Metabolism · 2006
    17. Prevalence of CYP21 Mutations and IRS1 Variant Among Women With Polycystic Ovary Syndrome and Adrenal Androgen Excess Fertility and Sterility · 2005
    18. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004