Genetic Variants Associated with Hyperandrogenemia in PCOS Pathophysiology

    February 2018 in “ Genetics research international ”
    Roshan Dadachanji, Nuzhat F. Shaikh, Srabani Mukherjee
    Studysummary This review summarizes the influence of gene polymorphisms on genetic predisposition to polycystic ovary syndrome, but reports no new experimental or clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 12

    1. Common Variants in the Sex Hormone-Binding Globulin Gene Influence SHBG Levels in Women with Polycystic Ovary Syndrome Annals of Nutrition and Metabolism · 2015
    2. Polymorphism of CAG and GGN Repeats of Androgen Receptor Gene in Women with Polycystic Ovary Syndrome Reproductive Biomedicine Online · 2015
    3. Androgen Receptor Gene Polymorphism and Polycystic Ovary Syndrome 2012
    4. Common Variants in the Sex Hormone-Binding Globulin Gene (SHBG) and Polycystic Ovary Syndrome (PCOS) in Mediterranean Women Human Reproduction · 2012
    5. Polycystic Ovary Syndrome: Etiology, Pathogenesis, and Diagnosis Nature Reviews Endocrinology · 2011
    6. Polycystic Ovary Syndrome and Its Impact on Health Middle East Fertility Society Journal · 2010
    7. Polycystic Ovary Syndrome: A Complex Condition with Psychological, Reproductive, and Metabolic Manifestations That Impacts Health Across the Lifespan BMC Medicine · 2010
    8. Association of AR rs6152G/A Gene Polymorphism With Susceptibility to Polycystic Ovary Syndrome in Chinese Women Reproduction, Fertility and Development · 2010
    9. Androgen Receptor Gene CAG Repeat Polymorphism in Women with Polycystic Ovary Syndrome Fertility and Sterility · 2008
    10. Shorter CAG Repeats in the Androgen Receptor Gene May Enhance Hyperandrogenicity in Polycystic Ovary Syndrome Gynecological Endocrinology · 2008
    11. Fetal Programming of Polycystic Ovary Syndrome by Androgen Excess: Evidence from Experimental, Clinical, and Genetic Association Studies The Journal of Clinical Endocrinology and Metabolism · 2006
    12. Androgen Excess Is the Key Element in Polycystic Ovary Syndrome Fertility and Sterility · 2003