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    Glossary CYP11A1

    enzyme converting cholesterol to pregnenolone, initiating steroid hormone production

    CYP11A1, also known as Cytochrome P450 Family 11 Subfamily A Member 1 or P450scc, is an enzyme crucial for the production of steroid hormones. It catalyzes the conversion of cholesterol to pregnenolone, the first step in the biosynthesis of all steroid hormones, which are vital for various bodily functions including stress response, immune function, and regulation of inflammation.

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    Research 10 of 437

    1. Intratumoral <i>De Novo</i> Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors Cancer research · 2011 · 402 citations
    2. The significance of CYP11A1 expression in skin physiology and pathology Molecular and Cellular Endocrinology · 2021 · 91 citations
    3. Association of Cyp11a Gene with Polycystic Ovarian Syndrome Patients in Lahore, Pakistan Pakistan Journal of Health Sciences · 2025
    4. Investigation of variants of the aromatase gene (CYP19A1) in female pattern hair loss British Journal of Dermatology · 2011 · 15 citations
    5. The Associations of Androgen-Related Genes CYP21A2 and CYP19A1 with Severe Acne Vulgaris in Patients from Southwest China Clinical Cosmetic and Investigational Dermatology · 2021 · 10 citations
    6. Association of Single Nucleotide Polymorphisms in the CYP19A1 Gene with Female Pattern Hair Loss in a Chinese Population Dermatology · 2015 · 7 citations
    7. MitoQ upregulates CYP19A1 to protect dermal papilla cells from DHT-induced mitochondrial dysfunction and apoptosis in androgenetic alopecia Biochemical Pharmacology · 2026
    8. Coconut oil works as a gonadal feedback testosterone booster and increases pituitary aromatase (cyp19a1b) expression levels in fugu (Takifugu rubripes) Aquaculture · 2025
    9. Exploring the role of CYP19A1 single nucleotide polymorphisms in the pathogenesis of female pattern hair loss Egyptian Journal of Dermatology and Venerology · 2025
    10. MitoQ enhances CYP19A1 expression to stimulate WNT/β-catenin signaling pathway for promoting hair growth in androgenetic alopecia European Journal of Pharmacology · 2024
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