Search

for
Search:

Glossary CYP17A1

enzyme crucial for steroid hormone production

CYP17A1, also known as Cytochrome P450 17A1, is an enzyme that plays a crucial role in the production of steroid hormones. It is involved in the conversion of pregnenolone and progesterone into their 17-alpha-hydroxylated products, which are precursors for androgens and estrogens. This enzyme is essential for the synthesis of hormones that regulate various bodily functions, including metabolism, immune response, and sexual development.

Related Terms

Research

5 / 558 results

Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

research Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

402 citations , August 2011 in “Cancer research”

This study found that castration-resistant prostate cancers resistant to CYP17A1 inhibitors may still depend on steroids and could respond to therapies targeting de novo intratumoral steroid synthesis.

research The significance of CYP11A1 expression in skin physiology and pathology

91 citations , March 2021 in “Molecular and Cellular Endocrinology”

CYP11A1 is crucial for skin health and disease by producing important steroids.

research Investigation of variants of the aromatase gene (CYP19A1) in female pattern hair loss

15 citations , June 2011 in “British Journal of Dermatology”

This study observed a potential association between the CC genotype of rs4646 and female pattern hair loss, but the authors advise caution due to lack of experiment-wide significance and recommend replication.

research The Associations of Androgen-Related Genes CYP21A2 and CYP19A1 with Severe Acne Vulgaris in Patients from Southwest China

10 citations , March 2021 in “Clinical Cosmetic and Investigational Dermatology”

This study found that specific genetic variants in the CYP21A2 and CYP19A1 genes were associated with severe acne vulgaris among Han Chinese, particularly in male patients.

research Association of Single Nucleotide Polymorphisms in the CYP19A1 Gene with Female Pattern Hair Loss in a Chinese Population

7 citations , January 2015 in “Dermatology”

This study found that specific CYP19A1 gene SNPs were significantly associated with female pattern hair loss risk in a Chinese Han population.

View more "cyp17a1" in research →

Learn

1 / 801 results

learn myristoyl pentapeptide-17

View more "cyp17a1" in learn →

Community Join

— no results

Try a deeper search in community →

Experts

— no results

Try a deeper search in experts →

Clinics

— no results

Try a deeper search in clinics →