Fetal Programming of Polycystic Ovary Syndrome by Androgen Excess: Evidence from Experimental, Clinical, and Genetic Association Studies

    March 2006 in “ The Journal of Clinical Endocrinology and Metabolism ”
    Nectaria Xita, Agathocles Tsatsoulis
    Studysummary This review discusses the hypothesis that polycystic ovary syndrome may originate in fetal life due to prenatal androgen exposure, but reports no new clinical results.
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    Research cited in this study 8

    1. Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome Fertility and Sterility · 2004
    2. Developmental Origin of Polycystic Ovary Syndrome: A Hypothesis Journal of Endocrinology · 2002
    3. Adult Polycystic Ovary Syndrome Begins in Childhood Best Practice & Research Clinical Endocrinology & Metabolism · 2002
    4. Polymorphisms of the Androgen Receptor Gene and the Estrogen Receptor Beta Gene Are Associated with Androgen Levels in Women The Journal of Clinical Endocrinology and Metabolism · 2001
    5. Polymorphism of the Androgen Receptor Gene Is Associated with Male Pattern Baldness Journal of Investigative Dermatology · 2001
    6. A Prospective Study of the Prevalence of Polycystic Ovary Syndrome in Unselected Caucasian Women from Spain The Journal of Clinical Endocrinology and Metabolism · 2000
    7. Prevalence of Polycystic Ovary Syndrome in Unselected Black and White Women of the Southeastern United States: A Prospective Study The Journal of Clinical Endocrinology and Metabolism · 1998
    8. Polycystic Ovary Syndrome: Clinical and Biochemical Features New England journal of medicine/˜The œNew England journal of medicine · 1995