Management of Endocrine Disease: Hyperandrogenic States in Women - Pitfalls in Laboratory Diagnosis
February 2018
in “
European Journal of Endocrinology
”
hyperandrogenic states PCOS androgen-secreting tumors total testosterone immunoassays anti-testosterone monoclonal antibodies LC-MS/MS SHBG free testosterone free-hormone hypothesis androstenedione adrenal androgen excess 17-hydroxyprogesterone NCAH LH secretion polycystic ovary syndrome sex hormone-binding globulin liquid chromatography-mass spectrometry non-classic adrenal hyperplasia luteinizing hormone
Studysummary This review discusses the challenges in measuring testosterone for assessing androgen excess in women and emphasizes the importance of quality control in laboratory methods, but it reports no new clinical results.
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