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Glossary Kisspeptin

protein that triggers hormone release for puberty and fertility

Kisspeptin is a protein that plays a crucial role in the regulation of the reproductive system by triggering the release of hormones necessary for puberty and fertility. It acts on the hypothalamus in the brain to stimulate the secretion of gonadotropin-releasing hormone (GnRH), which in turn influences the production of sex hormones like estrogen and testosterone.

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Research

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research Kisspeptin and LH pulsatile temporal coupling in PCOS patients

49 citations , May 2018 in “Endocrine”

This study found that only eumenorrheic polycystic ovary syndrome patients showed a temporal coupling between kisspeptin and luteinizing hormone pulsatile secretions.

research An integrative view of mammalian seasonal neuroendocrinology

85 citations , May 2019 in “Journal of neuroendocrinology”

This review examines the neuroendocrine mechanisms underlying seasonal changes in mammals and highlights areas needing further research, reporting no new experimental results.

research In Search of New Therapeutics—Molecular Aspects of the PCOS Pathophysiology: Genetics, Hormones, Metabolism and Beyond

44 citations , September 2020 in “International Journal of Molecular Sciences”

This review discusses the disruption of hormonal and metabolic rhythms in polycystic ovary syndrome and explores potential drug targets to address its molecular causes, without providing new clinical results.

research Neuroendocrine Determinants of Polycystic Ovary Syndrome

19 citations , March 2022 in “International Journal of Environmental Research and Public Health”

This review covers the neuroendocrine aspects of polycystic ovary syndrome, focusing on hormones and neurotransmitters like GnRH and kisspeptin, but does not report new clinical findings.

research Where Have the Periods Gone? The Evaluation and Management of Functional Hypothalamic Amenorrhea

18 citations , January 2020 in “Journal of Clinical Research in Pediatric Endocrinology”

This review discusses the pathophysiology, diagnosis, and management of functional hypothalamic amenorrhea in adolescent girls and reports no new clinical results.

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