research Genetic, Hormonal, and Metabolic Aspects of PCOS: An Update
The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.
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research Clinical Exome Sequencing Unveils the Genetic Landscape of Polycystic Ovarian Syndrome Focusing on Lean and Obese Phenotypes: Implications for Cost-Effective Diagnosis and Personalized Treatment
Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.
research Genetically Modified Laboratory Mice with Sebaceous Glands Abnormalities
Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research An Integrative View of Mammalian Seasonal Neuroendocrinology
The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.
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5 / 23 resultscommunity 3 month progress on Topical Minoxidil/Finasteride (Hims), oils, and derma-rolling
This user has been using a combination of topical Minoxidil and Finasteride, oils, biotin, vitamins D and K, and derma-rolling for 3 months to help reduce hair loss. They have experienced some progress but are still looking for more recommendations from others.
community My eyelashes and eyebrows on oral min
User Crazy-Signature930 shares progress on oral minoxidil for eyelashes and eyebrows. Others comment on the impressive results and ask about side effects and duration of use.
community PSA: Fin/Dut are NON-NEGOTIABLE
Finasteride and dutasteride are essential for stopping hair loss, while natural remedies are ineffective. Minoxidil can be added if needed, but blocking DHT is crucial.
community Started aggressively losing my hair at 16 and I'm now 30
The user started losing their hair at 16 and got a hair transplant. They used Minoxidil and finasteride as treatments. The transplant has held up well and they have not experienced graft loss.
community Long-term risks of finasteride are overplayed, here's why (a comprehensive review on the available research)
Finasteride's long-term risks are often exaggerated; studies showing negative effects typically involve high doses or animal subjects. For those taking 1mg daily for hair loss, there is no significant evidence of severe side effects.