Animal Models and the Developmental Origins of Polycystic Ovary Syndrome: Increasing Evidence for the Role of Androgens in Programming Reproductive and Metabolic Dysfunction

    May 2012 in “ Endocrinology ”
    Stephen Franks
    Studysummary This review discusses the etiology of polycystic ovary syndrome, emphasizing the role of genetic and environmental factors, and reports no new experimental findings.
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    Research cited in this study 5

    1. Consensus on Women's Health Aspects of Polycystic Ovary Syndrome: The Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group Fertility and sterility · 2011
    2. Ovarian Morphology Is a Marker of Heritable Biochemical Traits in Sisters with Polycystic Ovaries The Journal of Clinical Endocrinology and Metabolism · 2008
    3. Serum Levels of Retinol-Binding Protein 4 and Adiponectin in Women with Polycystic Ovary Syndrome: Associations with Visceral Fat but No Evidence for Fat Mass-Independent Effects on Pathogenesis in This Condition The Journal of Clinical Endocrinology & Metabolism · 2008
    4. Developmental Origin of Polycystic Ovary Syndrome: A Hypothesis Journal of Endocrinology · 2002
    5. Polycystic Ovary Syndrome: Clinical and Biochemical Features New England journal of medicine/˜The œNew England journal of medicine · 1995