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    GlossaryHair Follicle Development

    process where hair follicles form and mature through cellular events

    Hair follicle development, also known as hair follicle morphogenesis, is the process by which hair follicles form and mature. This involves a complex interplay of genetic, molecular, and cellular events that begin in the embryonic stage and continue through life. Key stages include the initiation of follicle placodes, the formation of hair germs, and the differentiation of various cell types that make up the follicle, ultimately leading to the production of hair shafts.

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      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn KY19382

      compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

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      community Keratin microspheres - breakthrough

      in Research/Science  13 upvotes 8 months ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Anyone Try Microneedling with Exosomes/AAPE?

      in Microneedling  2 upvotes 2 years ago
      User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

      community 22 years since the last major development

      in Technology  50 upvotes 3 years ago
      The conversation discusses the lack of significant advancements in hair loss treatments since the introduction of finasteride 22 years ago, with many expressing frustration over the failure of new projects and skepticism about future developments. Some users mention hair transplants and other potential alternatives like Alfatradiol and Fluridil, but acknowledge finasteride's dominance in the market due to its effectiveness and affordability.