48 citations
,
September 2011 in “British Journal of Dermatology” This study found that DNA methylation and histone modification status were altered in peripheral blood mononuclear cells of patients with alopecia areata, suggesting these changes may contribute to the disease's pathological immune responses.
1 citations
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July 2011 in “Hair transplant forum international” This article reports increased DNA methylation of the androgen receptor gene in the occipital hair follicles of men with androgenetic alopecia but presents no clinical results.
179 citations
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July 2016 in “Nature Reviews Molecular Cell Biology” This review examines how epigenetic dysregulation affects adult stem cell function, noting that impacts range from minor to serious disruptions in tissue homeostasis and potential cancer development.
2 citations
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January 2015 in “Elsevier eBooks” This review discusses current research on epigenetic changes in autoimmune skin diseases like vitiligo and alopecia areata, noting that the field is still developing and lacks extensive analysis.
January 2025 in “Stem Cells International” In this review, researchers discuss the role of epigenetic modifications in epidermal stem cells' decline during skin aging and identify potential interventions targeting these disruptions, suggesting significant possibilities for antiaging strategies and dermatological treatments.