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GlossaryEpigenomics

study of chemical changes affecting gene expression without altering DNA

Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, which influence gene activity without altering the DNA sequence. These modifications, such as DNA methylation and histone modification, can affect how genes are turned on or off and play a crucial role in development, disease, and environmental responses.

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All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration

research All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration

January 2018 in “Stem cell biology and regenerative medicine”

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

research Immunological Profile of Patients with Down Syndrome and Alopecia Areata

1 citations, January 2015 in “Advanced techniques in biology & medicine”

Down Syndrome patients with Alopecia Areata often have hypothyroidism and specific immune abnormalities.

Clinical Exome Sequencing Unveils the Genetic Landscape of Polycystic Ovarian Syndrome Focusing on Lean and Obese Phenotypes: Implications for Cost-Effective Diagnosis and Personalized Treatment

research Clinical Exome Sequencing Unveils the Genetic Landscape of Polycystic Ovarian Syndrome Focusing on Lean and Obese Phenotypes: Implications for Cost-Effective Diagnosis and Personalized Treatment

June 2024 in “Research Square (Research Square)”

Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

research The Agouti Mouse Model: An Epigenetic Biosensor for Nutritional and Environmental Alterations on the Fetal Epigenome

231 citations, July 2008 in “Nutrition reviews”

Diet changes can protect against harmful environmental effects on fetal development.

research Genome-Wide Association Study in Japanese Females Identifies Fifteen Novel Skin-Related Trait Associations

58 citations, June 2018 in “Scientific reports”

Researchers found 15 new genetic links to skin traits in Japanese women.

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community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 56 upvotes 3 days ago

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 month ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community abusing caffeine boosts DHT levels!

in Research/Science 1 upvotes 1 month ago

Caffeine intake may increase DHT levels, but its impact on hair loss is minimal compared to genetic factors. Excessive caffeine can cause health issues, and its effects on hair loss are not directly applicable to humans based on rat studies.

community My hair after 3 steroid cycles

in Progress Pictures 25 upvotes 4 months ago

A user shared their hair progress after three steroid cycles, using 5% minoxidil and 100mg RU58841 daily. They are considering a hair transplant due to paranoia about shedding.

community Had a son while being on FIN, MUST READ

in Finasteride/Dutasteride 619 upvotes 1 year ago

A user shared his experience of having two healthy children while continuously using finasteride (Fin) for hair loss, challenging fears about its potential impact on fetal development. The discussion that followed included various perspectives, with some users sharing similar experiences, others expressing concerns about potential risks, and some emphasizing the need for more substantial evidence before drawing conclusions.

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