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GlossaryEpigenomics

study of chemical changes affecting gene expression without altering DNA

Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, which influence gene activity without altering the DNA sequence. These modifications, such as DNA methylation and histone modification, can affect how genes are turned on or off and play a crucial role in development, disease, and environmental responses.

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All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration

research All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration

January 2018 in “Stem cell biology and regenerative medicine”

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

research Research Progress on the Molecular Mechanism of Poultry Feather Follicle Development

August 2025 in “Current Issues in Molecular Biology”

Key pathways like WNT, EGF, FGF, SHH, and BMP regulate poultry feather growth, with BMP inhibiting it.

research Immunological Profile of Patients with Down Syndrome and Alopecia Areata

1 citations , January 2015 in “Advanced techniques in biology & medicine”

Down Syndrome patients with Alopecia Areata often have hypothyroidism and specific immune abnormalities.

Clinical Exome Sequencing Unveils the Genetic Landscape of Polycystic Ovarian Syndrome Focusing on Lean and Obese Phenotypes: Implications for Cost-Effective Diagnosis and Personalized Treatment

research Clinical Exome Sequencing Unveils the Genetic Landscape of Polycystic Ovarian Syndrome Focusing on Lean and Obese Phenotypes: Implications for Cost-Effective Diagnosis and Personalized Treatment

June 2024 in “Research Square (Research Square)”

Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

research The Agouti Mouse Model: An Epigenetic Biosensor for Nutritional and Environmental Alterations on the Fetal Epigenome

231 citations , July 2008 in “Nutrition reviews”

Diet changes can protect against harmful environmental effects on fetal development.

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community My Delusional Hope - This page becomes irrelevant in 2030s

in Chat 51 upvotes 1 month ago

People are hopeful for a permanent hair loss solution by the 2030s, considering options like hair cloning and treatments like pp405. Synthetic hair transplants have been attempted but are not effective long-term.

community 3.5 months on minoxidil 5% (twice a day) before and after

in Progress Pictures 457 upvotes 1 month ago

A user shared progress pictures showing significant hair regrowth after 3.5 months of using 5% minoxidil twice a day. Some users expressed skepticism, suggesting a possible hair transplant, while others shared similar positive experiences with minoxidil, sometimes combined with biotin or other treatments.

community Sugar and Hair loss connections

in Research/Science 41 upvotes 6 months ago

High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 58 upvotes 1 year ago

Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hair loss.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

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