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    GlossaryEpigenomics

    study of chemical changes affecting gene expression without altering DNA

    Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, which influence gene activity without altering the DNA sequence. These modifications, such as DNA methylation and histone modification, can affect how genes are turned on or off and play a crucial role in development, disease, and environmental responses.

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      community Had a son while being on FIN, MUST READ

      in Finasteride/Dutasteride  618 upvotes 11 months ago
      A user shared his experience of having two healthy children while continuously using finasteride (Fin) for hair loss, challenging fears about its potential impact on fetal development. The discussion that followed included various perspectives, with some users sharing similar experiences, others expressing concerns about potential risks, and some emphasizing the need for more substantial evidence before drawing conclusions.

      community How much does diet affect hair loss?

      in Chat  47 upvotes 11 months ago
      The conversation suggests that changing diet and lifestyle has little to no effect on male pattern baldness (MPB), which is largely determined by genetics. Some individuals noted personal improvements in hair condition with healthier diets, but the consensus is that diet alone cannot prevent or reverse MPB.

      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community Oral or topical finasteride? .

      in Chat  12 upvotes 2 weeks ago
      A user is deciding between oral and topical finasteride for hair loss, noting oral finasteride's ease of use but broader effects. Another user simply recommends oral finasteride.