Epigenetics and Other Autoimmune Skin Diseases

January 2015 in “ Elsevier eBooks ”

Ming Zhao, Ruifang Wu, Qianjin Lu

epigenetics DNA methylation histone modifications microRNA autoimmune skin diseases systemic lupus erythematosus systemic scleroderma psoriasis vitiligo alopecia areata dermatomyositis pemphigus vulgaris lupus scleroderma pemphigus

TLDR Epigenetic changes contribute to autoimmune skin diseases.

Epigenetic mechanisms, such as DNA methylation, histone modifications, and microRNA, played a crucial role in gene expression regulation and were implicated in the development of various diseases, including autoimmune skin disorders. Dysregulation of these mechanisms, influenced by environmental, dietary, and mental factors, could lead to conditions like systemic lupus erythematosus, systemic scleroderma, and psoriasis. Although research on epigenetic changes in vitiligo, alopecia areata, dermatomyositis, and pemphigus vulgaris was still emerging, this review highlighted the importance of understanding these modifications to better comprehend and potentially treat these diseases.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 862 upvotes 3 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

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community Long term finasteride users; Did you notice any improvement after 2 years?

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Long term Finasteride users and whether or not they have noticed improvements after two years of use, with other treatments such as Minoxidil and dermarolling also discussed. Some replies suggest that improvement is possible even beyond the two year mark while others caution against believing studies backed by the Post-Finasteride Foundation.

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in Finasteride/Dutasteride 103 upvotes 6 months ago

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community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

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