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GlossaryPemphigus (Pemphigus Vulgaris)

rare autoimmune disorder causing skin and mucous membrane blisters

Pemphigus is a rare autoimmune disorder where the body's immune system mistakenly attacks the proteins in the skin and mucous membranes, leading to painful blisters and sores. These blisters can rupture easily, causing open wounds that are prone to infection. Treatment often involves immunosuppressive medications to reduce the immune system's activity.

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research Miniaturization of Sebaceous Glands: A Novel Histopathological Finding in Pemphigus Vulgaris and Pemphigus Foliaceus of the Scalp

9 citations , June 2017 in “Journal of Cutaneous Pathology”

People with pemphigus vulgaris and pemphigus foliaceus often have smaller sebaceous glands on their scalp.

research The Role of Natural Killer Cells in Autoimmune Blistering Diseases

24 citations , September 2011 in “Autoimmunity”

Natural killer cells play a key role in autoimmune skin diseases like pemphigus vulgaris.

research Acantholytic Hair Casts: A Dermoscopic Sign of Pemphigus Vulgaris of the Scalp

15 citations , January 2012 in “International Journal of Trichology”

Hair casts on the scalp may be a sign of ongoing pemphigus vulgaris and could suggest a need to adjust treatment.

research Persistent Pemphigus Vulgaris and Pemphigus Foliaceus Showing Features of Tufted Hair Folliculitis on the Scalp

March 2019 in “Nasza Dermatologia Online”

A rare scalp condition with hair loss was correctly diagnosed and treated, leading to hair regrowth.

research Pseudo Pemphigus Phenotypes in Mice with Inactivated Desmoglein 3

5 citations , October 2015 in “The American journal of pathology”

Mice with a mutated Dsg3 gene showed severe symptoms but not the typical blistering of pemphigus vulgaris.

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