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    Glossary Autoimmune Skin Diseases

    immune system attacks skin, causing inflammation and abnormalities

    Autoimmune Skin Diseases, also known as Autoimmune Dermatological Disorders, are conditions where the body's immune system mistakenly attacks its own skin cells, leading to inflammation, rashes, blisters, or other skin abnormalities. Examples include psoriasis, vitiligo, and lupus erythematosus. These diseases can cause significant discomfort and may require treatments like immunosuppressive medications to manage symptoms.

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      research Tyrosine Kinases in Autoimmune and Inflammatory Skin Diseases

      88 citations , August 2019 in “Frontiers in immunology”
      This review discusses the role of tyrosine kinase signaling pathways in autoimmune and inflammatory skin diseases and reports no new clinical results, highlighting ongoing research into small-molecule tyrosine kinase inhibitors as potential treatments.
      Oxidative Stress and Autoimmune Skin Disease

      research Oxidative stress and autoimmune skin disease

      73 citations , January 2013 in “European journal of dermatology/EJD. European journal of dermatology”
      This review examines current research on antioxidants in autoimmune skin diseases like alopecia areata and vitiligo, concluding with suggestions for future studies and treatment possibilities without reporting new clinical results.

      research Resident Memory T Cells in Autoimmune Skin Diseases

      50 citations , May 2021 in “Frontiers in immunology”
      This review discusses how tissue resident memory T cells contribute to autoimmune skin diseases like vitiligo and psoriasis, highlighting their role in continuous immune activation, and reports no new clinical results.

      research Immune-Molecular Link between Thyroid and Skin Autoimmune Diseases: A Narrative Review

      6 citations , September 2024 in “Journal of Clinical Medicine”
      This review explored the relationship between autoimmune thyroiditis and various autoimmune skin conditions, highlighting shared genetic markers and immunological mechanisms, such as disrupted immune tolerance and oxidative stress, which may contribute to the development of these disorders.

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      community fin 0.5 mg everday 6 months update

      in Finasteride/Dutasteride  28 upvotes 2 years ago
      The post discusses the experiences of individuals with diffuse hair thinning using finasteride, with many reporting no improvement or worsening conditions after 6 months. Various suggestions include persisting with the treatment, checking for underlying conditions, adding minoxidil for volume, adjusting dosage, and considering other potential causes like autoimmune responses and inflammation.

      community Has anyone here tried taking GLA supplements?

       1 upvotes 1 year ago
      GLA may help with hair loss due to its anti-inflammatory properties and 5ar enzyme inhibition. It's considered potentially more important than biotin, especially for those already using finasteride and dutasteride.

      community You will lose hair if your prostaglandins aren't in balance

       56 upvotes 1 year ago
      Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

      community Hair Loss & Lipids: Why you have sebderm, folliculitis, LPP, inflammation, etc...

       131 upvotes 1 year ago
      Excess sebum rich in cholesterol and triglycerides can lead to hair loss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.

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      learn Microneedling

      technique to create small wounds in skin to activate collagen production and hair growth

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Scalp Micropigmentation

      • Is scalp micropigmentation safe? Providers describe scalp micropigmentation as low-risk when a trained practitioner uses sterile single-use equipment, but that is a provider claim rather than a regulatory finding: pigment allergy, infection and colour change are documented risks of cosmetic tattooing.