Epigenetic Modifications May Explain the Relative Protection of Occipital Hair Follicles from Androgenetic Alopecia in Men

July 2011 in “ Hair transplant forum international ”

Mansi Patel, Rod Sinclair

epigenetic modifications DNA methylation androgenetic alopecia androgen receptor gene occipital hair follicles AGA AR gene

TLDR Epigenetic changes might protect occipital hair from male pattern baldness.

The document discussed the potential role of epigenetic modifications, specifically DNA methylation, in explaining why occipital hair follicles in men were relatively protected from androgenetic alopecia (AGA). The study suggested that increased DNA methylation of the androgen receptor (AR) gene in occipital hair follicles might contribute to this protection. This finding provided a possible explanation for the differential susceptibility of hair follicles to AGA, highlighting the importance of epigenetic factors in hair loss.

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Research cited in this study

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Evidence of Increased DNA Methylation of the Androgen Receptor Gene in Occipital Hair Follicles from Men with Androgenetic Alopecia

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

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