The Additive Effects of Minoxidil and Retinol on Human Hair Growth In Vitro

    Hyeon Gyun Yoo, In Ho Chang, Hyun-Mi Pyo … Se Kyu Kim
    Studysummary This study found that combining minoxidil and retinol additively promoted hair growth in vitro, enhancing Erk- and Akt-dependent pathways and preventing apoptosis in dermal papilla cells and keratinocytes.
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    Research cited in this study 12

    1. Hair Follicle Biology and Topical Minoxidil: Possible Mechanisms of Action Dermatology · 2009
    2. Biphasic Effects of Minoxidil on the Proliferation and Differentiation of Normal Human Keratinocytes Skin Pharmacology and Physiology · 2009
    3. Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle Journal of Dermatological Science · 2004
    4. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    5. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    6. Minoxidil Increases 17β-Hydroxysteroid Dehydrogenase and 5α-Reductase Activity in Cultured Human Dermal Papilla Cells from Balding Scalp Journal of Dermatological Science · 1999
    7. Hair Follicle Elongation in Organ Culture of Skin from Newborn and Adult Mice Journal of Dermatological Science · 1998
    8. Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells British Journal of Dermatology · 1998
    9. Inhibitory Effects of bFGF, VEGF, and Minoxidil on Collagen Synthesis by Cultured Hair Dermal Papilla Cells Archives of Dermatological Research · 1996
    10. Human Hair Growth In Vitro Journal of Cell Science · 1990
    11. Minoxidil Stimulates Mouse Vibrissae Follicles in Organ Culture Journal of Investigative Dermatology · 1989
    12. Retinoids: Compounds Important to Hair Growth Clinics in dermatology · 1988

    Related research 2

    1. The Additive Effects of Minoxidil and Retinol on Human Hair Growth In Vitro Biological & Pharmaceutical Bulletin · 2007
    2. Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle Journal of Dermatological Science · 2004