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GlossaryPhosphorylation

addition of a phosphate group to a molecule

Phosphorylation is a biochemical process where a phosphate group is added to a molecule, such as a protein or a nucleotide. This modification can change the molecule's function, activity, or location, and is crucial in regulating various cellular processes, including metabolism, cell signaling, and growth. For example, in the context of hair biology, phosphorylation can influence the activity of proteins involved in hair growth and follicle development.

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research The Complex Relationship Between TFEB Transcription Factor Phosphorylation and Subcellular Localization

344 citations, May 2018 in “EMBO journal”

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

Functional Identification of the Phosphorylation Sites of Arabidopsis PIN-FORMED3 for Its Subcellular Localization and Biological Role

research Functional Identification of the Phosphorylation Sites of Arabidopsis PIN-FORMED3 for Its Subcellular Localization and Biological Role

47 citations, April 2012 in “The Plant Journal”

Phosphorylation of certain parts of the PIN3 protein is crucial for its role in plant root growth and response to gravity.

research Wheat Sprout Extract Stimulates Cell Proliferation via Phosphorylation of ERK and Akt in Human Dermal Papilla Cells

June 2017 in “Yakakoeji/Yaghag hoeji”

Wheat sprout extract boosts hair cell growth by activating specific proteins.

research FLCN, A Novel Autophagy Component, Interacts With GABARAP And Is Regulated By ULK1 Phosphorylation

60 citations, July 2014 in “Autophagy”

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

research HB-EGF Improves the Hair Regenerative Potential of Adipose-Derived Stem Cells via ROS Generation and Hck Phosphorylation

20 citations, December 2019 in “International Journal of Molecular Sciences”

HB-EGF boosts the hair growth ability of stem cells, making it a potential hair loss treatment.

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community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 732 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community Wait, so retinol actually helps with hair growth? I heard it was the other way around a while ago and just accepted it..

in Treatment 6 upvotes 5 years ago

Retinol can help with hair growth, contrary to previous beliefs. Treatments discussed include Minoxidil, finasteride, and RU58841.

community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 122 upvotes 6 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community 1 year fin 1mg and minox. can see some density reclaimed

in Update 562 upvotes 3 years ago

User shared 1-year progress using finasteride 1mg and minoxidil, regaining hair density. Others praised the improvement and asked about side effects and additional treatments.