Wheat Sprout Extract Stimulates Cell Proliferation via Phosphorylation of ERK and Akt in Human Dermal Papilla Cells

    June 2017 in “ Yakakoeji/Yaghag hoeji
    Seol-a Park, Myoung-hee In, Won-Hong Woo, Yeun‐Ja Mun
    TLDR Wheat sprout extract boosts hair cell growth by activating specific proteins.
    The study investigated the effects of Wheat Sprout MeOH extract (WSM) on cell proliferation in human hair dermal papilla cells (HHDPCs). It was found that WSM increased cell proliferation more than minoxidil. This increase was associated with the phosphorylation of ERK and Akt proteins. The use of specific inhibitors (PD98059 for ERK and LY294002 for Akt) reduced the WSM-induced cell proliferation, indicating that WSM stimulated cell proliferation through the activation of ERK and Akt pathways.
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