Minoxidil Increases 17β-Hydroxysteroid Dehydrogenase and 5α-Reductase Activity in Cultured Human Dermal Papilla Cells from Balding Scalp

    February 1999 in “ Journal of Dermatological Science ”
    Toshihiro Sato, Taketsugu Tadokoro, Tadashige Sonoda … Susumu Takayasu
    Studysummary This study found that minoxidil increased 17ß-hydroxysteroid dehydrogenase activity by nearly 40% in dermal papilla cells from balding scalps but not in nonbalding scalp cells or dermal fibroblasts.
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    Research cited in this study 3

    1. The Therapeutic Use of Topical Minoxidil Dermatologic Clinics · 1990
    2. Reversal of Baldness in Patient Receiving Minoxidil for Hypertension The New England Journal of Medicine · 1980
    3. Minoxidil in Resistant Hypertension The Lancet · 1977

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