Azelaic Acid
Where to find Azelaic Acid
Tracking 26 topical products and 1 raw product by companies like MV supplements , Manual, Minoxidil Express and MinoxidilMax. View all 27 products »Azelaic acid is a naturally occurring dicarboxylic acid found in grains like wheat, rye, and barley. It's primarily known for its use in dermatology, particularly in treating mild to moderate acne and rosacea. Azelaic acid has antimicrobial and anti-inflammatory properties, making it effective in reducing skin bacteria, inflammation, and keratin buildup that can lead to acne. Its utility extends beyond these conditions, gaining interest for its potential role in hair loss treatment.
In the context of hair loss, azelaic acid's mechanism of action is believed to involve the inhibition of the enzyme 5-alpha-reductase. This enzyme converts testosterone into dihydrotestosterone (DHT), a hormone that plays a crucial role in androgenetic alopecia, a common form of hair loss. By potentially reducing DHT levels, azelaic acid may help minimize its detrimental effects on hair follicles, which include miniaturization and subsequent hair thinning and loss. Studies have also explored its role in promoting hair growth and improving hair density, often comparing it with established treatments like minoxidil.
Additionally, azelaic acid's antioxidant properties contribute to its therapeutic potential. It helps combat oxidative stress, a factor that can exacerbate hair loss. This multi-faceted approach to addressing hair loss at both hormonal and cellular levels makes azelaic acid an intriguing component in hair loss prevention and treatment strategies.
In the community, discussions about azelaic acid often revolve around its effectiveness when used in combination with other treatments like minoxidil and tretinoin. Users share their experiences with products containing azelaic acid, noting its benefits in hair regrowth and scalp health. While some users question the extent of its efficacy as a standalone treatment for hair loss, others view it as a valuable addition to their hair care regimen, particularly for its perceived safety and tolerability.
Research
20 / 258 results![Comparison of Azelaic Acid and Anthralin for the Therapy of Patchy Alopecia Areata](/images/research/f6d666e2-2fdd-47f5-b30e-8cf85a19354a/small/25015.jpg)
research Comparison of Azelaic Acid and Anthralin for the Therapy of Patchy Alopecia Areata
![Azelaic Acid in the Treatment of Acne in Adult Females: Case Reports](/images/research/e26c2dc1-c803-4a2e-bfc2-7c4568bcb57f/small/14472.jpg)
research Azelaic Acid in the Treatment of Acne in Adult Females: Case Reports
![BCL-2 and Bax Expression in Skin Flaps Treated with Finasteride or Azelaic Acid.](/images/research/8214603e-dec2-4a26-bac1-93b8ee6c127d/small/3241.jpg)
research BCL-2 and Bax Expression in Skin Flaps Treated with Finasteride or Azelaic Acid.
![Azelaic acid stimulates catalase activation and promotes hair growth through upregulation of Gli1 and Gli2 mRNA and Shh protein.](/images/research/4e2b0561-b5cc-454c-9aa4-7cd5bed556a5/small/23306.jpg)
research Azelaic acid stimulates catalase activation and promotes hair growth through upregulation of Gli1 and Gli2 mRNA and Shh protein.
![The pathogenesis of acne: How might azelaic acid act?](/images/research/df3aa31e-e3be-48ef-b3b8-2ae2ccd01134/small/28274.jpg)
research The pathogenesis of acne: How might azelaic acid act?
![Hair Follicle-Targeted Delivery of Azelaic Acid Micro/Nanocrystals Promote the Treatment of Acne Vulgaris](/images/research/114e5078-4063-4b15-ada6-25d06374e96a/small/37115.jpg)
research Hair Follicle-Targeted Delivery of Azelaic Acid Micro/Nanocrystals Promote the Treatment of Acne Vulgaris
![The multiple uses of azelaic acid in dermatology: mechanism of action, preparations, and potential therapeutic applications](/images/research/682ea0a3-3444-4fa5-a32d-4b2c0407f3df/small/36572.jpg)
research The multiple uses of azelaic acid in dermatology: mechanism of action, preparations, and potential therapeutic applications
![The Efficacy of Azelaic Acid 20% Cream in the Treatment of Scalp Alopecia Areata](/images/research/cd772075-ac40-4f16-b49d-b6784a0e5c65/small/23305.jpg)
research The Efficacy of Azelaic Acid 20% Cream in the Treatment of Scalp Alopecia Areata
![Comparison of the in vitro Demodex folliculorum killing activity of azelaic acid and permethrin](/images/research/2d904a6c-ee8d-4900-82a4-66da3d778ca7/small/16991.jpg)
research Comparison of the in vitro Demodex folliculorum killing activity of azelaic acid and permethrin
research A Study for Verification of Hair Growth Effect of Azelaic Acid and Vitamin B 6
![Efficacy and Safety of Topical 5% Azelaic Acid Solution Versus 2% Minoxidil Solution in the Treatment of Female Pattern Hair Loss](/images/research/010c7c59-b280-480b-b365-35386b9cb035/small/23304.jpg)
research Efficacy and Safety of Topical 5% Azelaic Acid Solution Versus 2% Minoxidil Solution in the Treatment of Female Pattern Hair Loss
research Comparative Study of Efficacy of Topical Minoxidil 5% and Combination of Topical Minoxidil 5%, Topical Azelaic Acid 1.5% and Topical Tretinoin 0.01% on the Basis of Dermoscopic Analysis in Androgenetic Alopecia
research Comparative Study of Efficacy of Topical Minoxidil 5% and Combination of Topical Minoxidil 5%, Topical Azelaic Acid 1.5% and Topical Tretinoin 0.01% on the Basis of Dermoscopic Analysis in Androgenetic Alopecia
research HIV and alopecia universalis
![Combination therapy profoundly improved skin flap survival by modulating KATP channels and nitric oxide](/images/research/c8e17109-674e-401f-9f46-82d2df41954e/small/17721.jpg)
research Combination therapy profoundly improved skin flap survival by modulating KATP channels and nitric oxide
![Efficacy of topical caffeine in male androgenetic alopecia](/images/research/9817163d-e3fd-481c-a94b-ac99b9173142/small/4084.jpg)
research Efficacy of topical caffeine in male androgenetic alopecia
![Frontal fibrosing alopecia and lichen planus pigmentosus: is there a link?](/images/research/1f6ff366-6356-45ba-9ced-d509d26aa302/small/28534.jpg)
research Frontal fibrosing alopecia and lichen planus pigmentosus: is there a link?
![A review of diagnosis and treatment of acne in adult female patients](/images/research/b08990d1-4e89-4c65-84c4-b0b81132db99/small/17916.jpg)
research A review of diagnosis and treatment of acne in adult female patients
![Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne](/images/research/009de2e0-f55c-4c10-a710-b214b5a3e96a/small/28538.jpg)
research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne
![Female type of adult acne: Physiological and psychological considerations and management](/images/research/e6f53ceb-8c9c-4af7-80cd-67844c8f6012/small/13721.jpg)