The Versatility of Azelaic Acid in Dermatology

July 2020 in “ Journal of Dermatological Treatment ”

Tamara Searle, Faisal R. Ali, Firas Al‐Niaimi

azelaic acid rosacea melasma acne vulgaris hidradenitis suppurativa keratosis pilaris male androgenic alopecia

Studysummary This review found the strongest evidence supporting azelaic acid's use in treating rosacea, with somewhat less evidence for its effectiveness in melasma and acne vulgaris, and weaker support for its use in conditions like hidradenitis suppurativa and keratosis pilaris.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

Azelaic acid was found to have versatile applications in dermatology due to its anti-inflammatory and antioxidant properties. The review of literature indicated the strongest evidence for its efficacy in treating rosacea, with moderate support for its off-label use in melasma and acne vulgaris. There was weaker evidence for its effectiveness in conditions like hidradenitis suppurativa, keratosis pilaris, and male androgenic alopecia. Azelaic acid, whether used alone or in combination with other treatments, was considered a well-tolerated and safe option for various dermatological conditions.

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