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GlossaryFollicular Hyperkeratosis (Keratosis Pilaris)

condition where hair follicles clog with keratin, causing bumps

Follicular Hyperkeratosis, also known as Keratosis Pilaris, is a common skin condition where hair follicles become clogged with keratin, a protein found in the skin. This results in small, rough bumps, often on the arms, thighs, cheeks, or buttocks, giving the skin a sandpaper-like texture. It is generally harmless but can be cosmetically concerning for some individuals.

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research Clinical Findings, Cutaneous Pathology, and Response to Therapy in 21 Patients With Keratosis Pilaris Atrophicans

78 citations, April 1994 in “Archives of dermatology”

The study found that Keratosis Pilaris Atrophicans is a genetic skin condition that starts in childhood, involves inflammation and scarring, and current treatments are only somewhat effective.

research Sebaceous Gland, Hair Shaft, and Epidermal Barrier Abnormalities in Keratosis Pilaris with and without Filaggrin Deficiency

23 citations, February 2015 in “The American journal of pathology”

Keratosis pilaris is often linked to genetic mutations and causes skin and hair abnormalities, regardless of those mutations.

research Treatment of Keratosis Pilaris With 810-nm Diode Laser

20 citations, November 2014 in “JAMA dermatology”

The 810-nm diode laser improves skin texture in keratosis pilaris but not redness.

research Nilotinib-Induced Keratosis Pilaris

19 citations, April 2016 in “Case Reports in Dermatology”

Nilotinib can cause keratosis pilaris, a skin condition.

research Triad of Keratosis Pilaris, Ulerythema Ophryogenes, and 18p Monosomy: Zouboulis Syndrome

15 citations, May 2014 in “Journal of dermatology”

Zouboulis syndrome is a rare condition that helps diagnose monosomy 18p early.

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community My skin is always dry and flakes like chalk (25)

in Transgender 6 upvotes 8 months ago

The user underwent a biopsy two years ago and was diagnosed with keratosis pilaris, leading to hair issues. They tried treatments including Minoxidil, betamethasone, lymecycline, topical Accutane, and dutasteride, as well as diet changes, without improvement in hair thickness or skin dryness.

community My Experience and a Discourse on "DUPA"

in Treatment 9 upvotes 6 months ago

The user discusses their hair loss experience, exploring various hypotheses including thyroid levels, vitamin D, DHEA, nutritional deficiency, diabetes, seborrheic dermatitis, lack of nutrition to hair follicles, chronic inflammation, female pattern hair loss causes, cortisol, and prolactin levels. They are currently using finasteride, beta-sitosterol, and have tried topical dutasteride and microneedling therapy.

community here is why isotretinoin might cause hair loss and maybe why dupa happens.

in Research/Science 7 upvotes 1 year ago

Isotretinoin may cause hair loss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hair loss.

community The hardest hair protocol ever!

in Research/Science 10 upvotes 2 years ago

The user is using RU58841, finasteride, dutasteride, and minoxidil to slow down aggressive hair loss but is still experiencing hair shedding due to high testosterone levels. They plan to use ostarine to lower testosterone and prevent hair loss while maintaining muscle mass, and will continue using the other treatments.

community 22M Fin and min everyday for 10 months, looks like my right temple is still receding

in Finasteride/Dutasteride 67 upvotes 1 year ago

The user is seeking opinions on their hair loss, specifically the receding of their right temple. They are considering switching to Dutasteride but are unsure if it will help. Other users suggest that their hairline has improved with the use of Finasteride and Minoxidil. One user mentions using RU58841 to thicken their hairline.

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