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GlossaryFollicular Hyperkeratosis (Keratosis Pilaris)

condition where hair follicles clog with keratin, causing bumps

Follicular Hyperkeratosis, also known as Keratosis Pilaris, is a common skin condition where hair follicles become clogged with keratin, a protein found in the skin. This results in small, rough bumps, often on the arms, thighs, cheeks, or buttocks, giving the skin a sandpaper-like texture. It is generally harmless but can be cosmetically concerning for some individuals.

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research Clinical Findings, Cutaneous Pathology, and Response to Therapy in 21 Patients With Keratosis Pilaris Atrophicans

78 citations , April 1994 in “Archives of dermatology”

The study found that Keratosis Pilaris Atrophicans is a genetic skin condition that starts in childhood, involves inflammation and scarring, and current treatments are only somewhat effective.

research Sebaceous Gland, Hair Shaft, and Epidermal Barrier Abnormalities in Keratosis Pilaris with and without Filaggrin Deficiency

23 citations , February 2015 in “The American journal of pathology”

Keratosis pilaris is often linked to genetic mutations and causes skin and hair abnormalities, regardless of those mutations.

research Treatment of Keratosis Pilaris With 810-nm Diode Laser

20 citations , November 2014 in “JAMA dermatology”

The 810-nm diode laser improves skin texture in keratosis pilaris but not redness.

research Nilotinib-Induced Keratosis Pilaris

19 citations , April 2016 in “Case Reports in Dermatology”

Nilotinib can cause keratosis pilaris, a skin condition.

research Keratosis Pilaris and Scarring Alopecia

18 citations , March 1992 in “Archives of Dermatology”

The man's scarring alopecia and skin issues did not improve with treatments.

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community My skin is always dry and flakes like chalk (25)

in Transgender 7 upvotes 1 year ago

The user underwent a biopsy two years ago and was diagnosed with keratosis pilaris, leading to hair issues. They tried treatments including Minoxidil, betamethasone, lymecycline, topical Accutane, and dutasteride, as well as diet changes, without improvement in hair thickness or skin dryness.

community My Experience and a Discourse on "DUPA"

in Treatment 9 upvotes 1 year ago

The user discusses their hair loss experience, exploring various hypotheses including thyroid levels, vitamin D, DHEA, nutritional deficiency, diabetes, seborrheic dermatitis, lack of nutrition to hair follicles, chronic inflammation, female pattern hair loss causes, cortisol, and prolactin levels. They are currently using finasteride, beta-sitosterol, and have tried topical dutasteride and microneedling therapy.

community here is why isotretinoin might cause hair loss and maybe why dupa happens.

in Research/Science 7 upvotes 2 years ago

Isotretinoin may cause hair loss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hair loss.

community The hardest hair protocol ever!

in Research/Science 9 upvotes 3 years ago

The user is using RU58841, finasteride, dutasteride, and minoxidil to slow down aggressive hair loss but is still experiencing hair shedding due to high testosterone levels. They plan to use ostarine to lower testosterone and prevent hair loss while maintaining muscle mass, and will continue using the other treatments.

community Losing Hair on Dutasteride? You might have LPP

in Research/Science 94 upvotes 8 months ago

Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

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