Treatment of Keratosis Pilaris With 810-nm Diode Laser

November 2014 in “ JAMA dermatology ”

Omer Ibrahim, M. Ali Khan, Diana Bolotin, Meghan Dubina, Michael Nodzenski, Wareeporn Disphanurat, Rohit Kakar, Simon Yoo, Dennis Whiting, Dennis P. West, Emily Poon, Emir Veledar, Murad Alam

keratosis pilaris 810-nm diode laser skin texture roughness bumpiness erythema Fitzpatrick skin types inflammatory hyperpigmentation KP diode laser skin roughness skin bumps skin redness skin types hyperpigmentation

TLDR The 810-nm diode laser improves skin texture in keratosis pilaris but not redness.

The study evaluated the 810-nm diode laser for treating keratosis pilaris (KP) in a split-body, placebo-controlled randomized clinical trial with 23 patients (18 completed). Three laser treatments significantly improved skin texture and roughness/bumpiness (median score difference of 1, P = .004) but did not affect baseline erythema (P = .11). The combined score for erythema and roughness/bumpiness also showed significant improvement (P = .005). The laser was effective for KP in Fitzpatrick skin types I-III, though it did not address redness, indicating a need for combined treatments. Two participants experienced inflammatory hyperpigmentation, which resolved within three months. The study suggested the 810-nm diode laser as a promising treatment for nonerythematous KP, with further research needed for long-term benefits and effectiveness in darker skin types.

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