Cicatricial Alopecias

May 2017 in “ InTech eBooks ”

Ibrahim Halil Yavuz, Göknur Özaydın Yavuz, Serap Gunes Bilgili

Primary Cicatricial Alopecias PCA lichen planopilaris discoid lupus erythematosus folliculitis decalvans corticosteroids immunomodulatory drugs pseudopelade of Brocq central centrifugal cicatricial alopecia CCCA alopecia mucinosa keratosis follicularis spinulosa decalvans KFSD scarring alopecia cicatricial alopecia steroids immunosuppressants

TLDR Some hair loss disorders cause permanent loss due to scarring, and treatments like steroids don't always work well.

The document from 2017 provides an overview of Primary Cicatricial Alopecias (PCA), a group of disorders causing irreversible hair loss due to scarring from inflammation. It details the clinical features, diagnosis, and treatment of various PCAs, including lymphocytic types like lichen planopilaris and discoid lupus erythematosus, and neutrophilic types like folliculitis decalvans. Treatments range from corticosteroids to immunomodulatory drugs, with variable effectiveness. The document also describes other forms of cicatricial alopecia, such as classic pseudopelade of Brocq, central centrifugal cicatricial alopecia (CCCA), alopecia mucinosa, keratosis follicularis spinulosa decalvans (KFSD), and acne-related conditions. It notes the challenges in treatment, as many patients do not respond well and may relapse, underscoring the need for accurate diagnosis and comprehensive management.

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Research cited in this study

27 / 27 results

research Central Centrifugal Cicatricial Alopecia: Challenges and Solutions

37 citations , August 2016 in “Clinical, Cosmetic and Investigational Dermatology”

The document concludes that better treatments for CCCA are needed and more research is required to understand its causes related to hairstyling and genetics.

research Primary Scarring Alopecias

27 citations , January 2015 in “Current problems in dermatology”

The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.

Dissecting Cellulitis (Perifolliculitis Capitis Abscedens et Suffodiens): A Comprehensive Review Focusing on New Treatments and Findings of the Last Decade with Commentary Comparing the Therapies and Causes of Dissecting Cellulitis to Hidradenitis Suppurativa

research Dissecting Cellulitis (Perifolliculitis Capitis Abscedens et Suffodiens): A Comprehensive Review Focusing on New Treatments and Findings of the Last Decade with Commentary Comparing the Therapies and Causes of Dissecting Cellulitis to Hidradenitis Suppurativa

48 citations , January 2014 in “Dermatology Online Journal”

New treatments for Dissecting cellulitis show promise, but more research is needed to understand the disease and establish a standard treatment plan.

research Erosive Pustular Dermatosis of the Scalp Successfully Treated with Oral Prednisone and Topical Tacrolimus

16 citations , October 2013 in “Anais Brasileiros de Dermatologia”

Scalp condition healed with prednisone and tacrolimus.

research What's New in Cicatricial Alopecia?

16 citations , January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”

New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.

research Frontal Fibrosing Alopecia: A Review of 60 Cases

166 citations , April 2012 in “Journal of The American Academy of Dermatology”

Mostly postmenopausal Caucasian women get Frontal Fibrosing Alopecia, which often includes eyebrow loss and has limited treatment success.

research Primary Cicatricial Alopecia: Recent Advances in Understanding and Management

44 citations , November 2011 in “The Journal of Dermatology”

New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.

research Alopecia: Evaluation and Treatment

76 citations , July 2011 in “Clinical, Cosmetic and Investigational Dermatology”

The document concludes that proper diagnosis and FDA-approved treatments for different types of hair loss exist, but treatments for severe cases often fail and future improvements may focus on hair follicle stem cells.

research Frontal Fibrosing Alopecia: To Treat or Not to Treat?

29 citations , July 2010 in “Journal of Cutaneous Medicine and Surgery”

Treatments for Frontal Fibrosing Alopecia have not been proven effective.

research Central Centrifugal Cicatricial Alopecia: Past, Present, and Future

75 citations , March 2009 in “Journal of The American Academy of Dermatology”

CCCA is a hair loss type affecting African women, possibly caused by grooming and chemicals, with various treatments and needing more research.

research Frontal Fibrosing Alopecia: Clinical Presentations and Prognosis

155 citations , September 2008 in “British journal of dermatology/British journal of dermatology, Supplement”

FFA is more common in postmenopausal women, can affect younger women, and may stabilize over time.

research Folliculitis Decalvans: A Rare Inflammatory Scalp Disorder

112 citations , July 2008 in “Dermatologic Therapy”

Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.

research Lichen Planopilaris: Chronic Scarring Alopecia with Autoimmune Component

90 citations , July 2008 in “Dermatologic therapy”

Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.

research Central Centrifugal Cicatricial Alopecia

72 citations , July 2008 in “Dermatologic Therapy”

CCCA is a scarring hair loss condition mainly in African descent women, possibly caused by genetics and hairstyling, treated with gentle hair care and medications.

research Pseudopelade of Brocq: A Review of a Rare Hair Disorder Leading to Cicatricial Alopecia

39 citations , July 2008 in “Dermatologic Therapy”

Pseudopelade of Brocq is a unique hair loss condition, but its cause and development are still not fully understood.

research Diagnosis and Management of Primary Cicatricial Alopecia: Part II

32 citations , March 2008 in “SKINmed Dermatology for the Clinician”

Accurate diagnosis and tailored treatment are crucial for managing complex hair loss conditions.

research Diagnosis and Management of Primary Cicatricial Alopecia: Part I

42 citations , January 2008 in “SKINmed/Skinmed”

The article explains how to diagnose and manage certain types of scarring hair loss.

research Successful Treatment of Perifolliculitis Capitis Abscedens et Suffodiens With Combined Isotretinoin and Dapsone

22 citations , October 2007 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft”

Combining isotretinoin and dapsone effectively treated a challenging scalp condition.

research Graham Little-Piccardi-Lassueur Syndrome Associated with Androgen Insensitivity Syndrome (Testicular Feminization)

22 citations , June 2004 in “Journal of The European Academy of Dermatology and Venereology”

A woman had both Graham Little-Piccardi-Lassueur syndrome, causing hair loss, and complete androgen insensitivity syndrome, making her genetically male but physically female. This suggests androgens don't affect the hair loss condition.

research Ethnic Hair Update: Past and Present

73 citations , June 2003 in “Journal of the American Academy of Dermatology”

Dermatologists need to understand African American hair-care practices to better treat their hair and scalp disorders.

research Lichen Planopilaris and Autoimmune Thyroiditis

20 citations , November 2002 in “Journal of the European Academy of Dermatology and Venereology”

Lichen planopilaris may be linked to autoimmune thyroiditis.

research Pseudopelade of Brocq in Beard Area

24 citations , May 2000 in “Journal of the American Academy of Dermatology”

Pseudopelade can affect both the scalp and beard, causing hair loss.

research Folliculitis Decalvans Including Tufted Folliculitis: Clinical, Histological, and Therapeutic Findings

226 citations , February 1999 in “British Journal of Dermatology”

Folliculitis decalvans and tufted folliculitis are related, and a new treatment with rifampicin and clindamycin is effective.

research Postmenopausal Frontal Fibrosing Alopecia: A Frontal Variant of Lichen Planopilaris

329 citations , January 1997 in “Journal of the American Academy of Dermatology”

Frontal fibrosing alopecia is a hair loss condition in postmenopausal women, similar to lichen planopilaris, with ineffective treatments.

research Clinical Findings, Cutaneous Pathology, and Response to Therapy in 21 Patients With Keratosis Pilaris Atrophicans

78 citations , April 1994 in “Archives of dermatology”

The study found that Keratosis Pilaris Atrophicans is a genetic skin condition that starts in childhood, involves inflammation and scarring, and current treatments are only somewhat effective.

research Ichthyosis Follicularis With Alopecia and Photophobia

75 citations , September 1985 in “Archives of dermatology”

Two boys had a rare skin condition needing to be differentiated from similar disorders, with unclear inheritance due to few cases.

research Erosive Pustular Dermatosis of the Scalp

187 citations , May 1979 in “British Journal of Dermatology”

Topical steroids can manage chronic scalp pustules in elderly women.

Related Research

2 / 2 results

research Hair and Nail Conditions: Alopecia Evaluation

1 citations , June 2022 in “PubMed”

Alopecia causes hair loss and should be treated early, especially scarring types where hair cannot regrow.

research Acquired Scalp Alopecia: A Review

37 citations , May 1999 in “Australasian Journal of Dermatology”

Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.