Cicatricial Alopecias

May 2017 in “ InTech eBooks ”

Ibrahim Halil Yavuz, Göknur Özaydın Yavuz, Serap Gunes Bilgili

Primary Cicatricial Alopecias PCA lichen planopilaris discoid lupus erythematosus folliculitis decalvans corticosteroids immunomodulatory drugs pseudopelade of Brocq central centrifugal cicatricial alopecia CCCA alopecia mucinosa keratosis follicularis spinulosa decalvans KFSD scarring alopecia cicatricial alopecia steroids immunosuppressants

Studysummary This review discusses various types of primary cicatricial alopecias, categorized by the predominant type of inflammatory cells involved, and reports no new clinical results.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The document from 2017 provides an overview of Primary Cicatricial Alopecias (PCA), a group of disorders causing irreversible hair loss due to scarring from inflammation. It details the clinical features, diagnosis, and treatment of various PCAs, including lymphocytic types like lichen planopilaris and discoid lupus erythematosus, and neutrophilic types like folliculitis decalvans. Treatments range from corticosteroids to immunomodulatory drugs, with variable effectiveness. The document also describes other forms of cicatricial alopecia, such as classic pseudopelade of Brocq, central centrifugal cicatricial alopecia (CCCA), alopecia mucinosa, keratosis follicularis spinulosa decalvans (KFSD), and acne-related conditions. It notes the challenges in treatment, as many patients do not respond well and may relapse, underscoring the need for accurate diagnosis and comprehensive management.

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29 / 29 results

research Central Centrifugal Cicatricial Alopecia: Challenges and Solutions

37 citations , August 2016 in “Clinical, Cosmetic and Investigational Dermatology”

This article discusses central centrifugal cicatricial alopecia, highlighting its prevalence, potential genetic factors, and management challenges, but reports no new clinical conclusions and calls for further research.

research Primary Scarring Alopecias

27 citations , January 2015 in “Current problems in dermatology”

This article reviews various types of scarring alopecia, detailing their inflammatory characteristics, but presents no new clinical findings.

Dissecting Cellulitis (Perifolliculitis Capitis Abscedens et Suffodiens): A Comprehensive Review Focusing on New Treatments and Findings of the Last Decade with Commentary Comparing the Therapies and Causes of Dissecting Cellulitis to Hidradenitis Suppurativa

research Dissecting Cellulitis (Perifolliculitis Capitis Abscedens et Suffodiens): A Comprehensive Review Focusing on New Treatments and Findings of the Last Decade with Commentary Comparing the Therapies and Causes of Dissecting Cellulitis to Hidradenitis Suppurativa

48 citations , January 2014 in “Dermatology Online Journal”

This review examines various treatments for dissecting cellulitis, noting isotretinoin may offer the best chance for remission despite limited long-term data and calls for more clinical studies.

research Erosive Pustular Dermatosis of the Scalp Successfully Treated with Oral Prednisone and Topical Tacrolimus

16 citations , October 2013 in “Anais Brasileiros de Dermatologia”

In this case report, an elderly woman with erosive pustular dermatosis of the scalp showed complete closure of eroded areas after treatment with prednisone and topical tacrolimus, resulting in stable scarring alopecia.

research What's New in Cicatricial Alopecia?

16 citations , January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”

This review explores new theories, diagnostic tools, and management strategies for primary cicatricial alopecia but reports no new clinical findings.

research Frontal Fibrosing Alopecia: A Review of 60 Cases

166 citations , April 2012 in “Journal of The American Academy of Dermatology”

This study reviewed clinical data from 60 patients with frontal fibrosing alopecia and found increasing prevalence and generally poor response to treatment, with the cause remaining unclear.

research Primary Cicatricial Alopecia: Recent Advances in Understanding and Management

44 citations , November 2011 in “The Journal of Dermatology”

This review discusses recent advancements in the management and diagnosis of primary cicatricial alopecias but reports no new clinical results; emerging insights suggest sebaceous gland dysfunction may play a role in their etiopathogenesis.

research Alopecia: Evaluation and Treatment

76 citations , July 2011 in “Clinical, Cosmetic and Investigational Dermatology”

This review discusses clinical methods for diagnosing alopecia and examines current treatments for both cicatricial and noncicatricial forms but provides no new clinical results.

research Frontal Fibrosing Alopecia: To Treat or Not to Treat?

29 citations , July 2010 in “Journal of Cutaneous Medicine and Surgery”

This study reported no significant improvement in patients with frontal fibrosing alopecia treated with various therapeutic agents, highlighting the need for more evidence-based treatments, especially in those with active disease.

research Central Centrifugal Cicatricial Alopecia: Past, Present, and Future

75 citations , March 2009 in “Journal of The American Academy of Dermatology”

This review discusses the evolution and ongoing debate about the causes of central centrifugal cicatricial alopecia in African American women, without presenting new clinical findings.

research Frontal Fibrosing Alopecia: Clinical Presentations and Prognosis

155 citations , September 2008 in “British journal of dermatology/British journal of dermatology, Supplement”

This study observed that frontal fibrosing alopecia predominantly affects postmenopausal women, can be associated with lichen planus, and may lead to progressive hairline recession, though this progression is not consistent in all cases.

research Lichen Planopilaris: Chronic Scarring Alopecia with Autoimmune Component

90 citations , July 2008 in “Dermatologic therapy”

This article reviews lichen planopilaris, a chronic scarring alopecia, and explores recent treatment developments, but it reports no new clinical results.

research Folliculitis Decalvans: A Rare Inflammatory Scalp Disorder

112 citations , July 2008 in “Dermatologic Therapy”

This review outlines the diagnosis and management of folliculitis decalvans, an inflammatory scalp disorder, and highlights Staphylococcus aureus and immune response deficiencies as key factors in its development.

research Pseudopelade of Brocq: A Review of a Rare Hair Disorder Leading to Cicatricial Alopecia

39 citations , July 2008 in “Dermatologic Therapy”

This review provides a practical approach to diagnosing pseudopelade of Brocq and updates on treatment options but reports no new clinical results.

research Central Centrifugal Cicatricial Alopecia

72 citations , July 2008 in “Dermatologic Therapy”

This article reviews central centrifugal cicatricial alopecia in African-descent females, discussing possible causes, associated styling habits, and potential treatments, but reports no new clinical findings; the authors call for further research.

research Diagnosis and Management of Primary Cicatricial Alopecia: Part II

32 citations , March 2008 in “SKINmed Dermatology for the Clinician”

This review examines the clinical features, histology, and treatment options for various neutrophilic and mixed primary cicatricial alopecias, but presents no new data.

research Diagnosis and Management of Primary Cicatricial Alopecia: Part I

42 citations , January 2008 in “SKINmed/Skinmed”

This review article discusses the classification, epidemiology, diagnostic approach, and patient management of lymphocytic primary cicatricial alopecias, without reporting new clinical results.

research Successful Treatment of Perifolliculitis Capitis Abscedens et Suffodiens With Combined Isotretinoin and Dapsone

22 citations , October 2007 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft”

In this case study, combination therapy with dapsone and isotretinoin significantly improved perifolliculitis capitis abscedens et suffodiens, with the patient remaining symptom-free for six months on reduced medication.

research Graham Little-Piccardi-Lassueur Syndrome Associated with Androgen Insensitivity Syndrome (Testicular Feminization)

22 citations , June 2004 in “Journal of The European Academy of Dermatology and Venereology”

This case report identifies a novel association between Graham Little–Piccardi–Lassueur syndrome and complete androgen insensitivity syndrome, suggesting the influence of androgens in the alopecias accompanying the former may be limited.

research Ethnic Hair Update: Past and Present

73 citations , June 2003 in “Journal of the American Academy of Dermatology”

This article reviews common hair-care practices among African American patients and discusses how these practices relate to hair and scalp disorders, without presenting new clinical research.

research Lichen Planopilaris and Autoimmune Thyroiditis

20 citations , November 2002 in “Journal of the European Academy of Dermatology and Venereology”

Lichen planopilaris may be linked to autoimmune thyroiditis.

research Pseudopelade of Brocq in Beard Area

24 citations , May 2000 in “Journal of the American Academy of Dermatology”

This case report describes a patient with pseudopelade affecting both the scalp and beard area, highlighting the unusual presentation of a rare hair disorder.

research Folliculitis Decalvans Including Tufted Folliculitis: Clinical, Histological, and Therapeutic Findings

226 citations , February 1999 in “British Journal of Dermatology”

This study reported that a treatment regimen of oral rifampicin and clindamycin for 10 weeks effectively managed folliculitis decalvans, with most patients experiencing no recurrence after one or multiple courses.

research Postmenopausal Frontal Fibrosing Alopecia: A Frontal Variant of Lichen Planopilaris

329 citations , January 1997 in “Journal of the American Academy of Dermatology”

This study reports that progressive frontal fibrosing alopecia, a distinct and gradually stabilizing form of lichen planopilaris affecting elderly women and often involving eyebrow hair loss, lacks effective treatments.

research Postmenopausal Frontal Fibrosing Alopecia

325 citations , June 1994 in “Archives of Dermatology”

This study observed that progressive frontal recession in postmenopausal women may exhibit features of fibrosing alopecia, suggesting a distinct reaction pattern from typical lichen planopilaris.

research Clinical Findings, Cutaneous Pathology, and Response to Therapy in 21 Patients With Keratosis Pilaris Atrophicans

78 citations , April 1994 in “Archives of dermatology”

This study suggests genetic and clinical heterogeneity in keratosis pilaris atrophicans, with variations in inheritance patterns, severity, and response to treatment among 21 individuals observed.

research Ichthyosis Follicularis With Alopecia and Photophobia

75 citations , September 1985 in “Archives of dermatology”

This report of ichthyosis follicularis in two boys discusses the challenges of distinguishing it from similar disorders, noting its rarity and unclear inheritance pattern without providing new clinical results.

research Erosive Pustular Dermatosis of the Scalp

187 citations , May 1979 in “British Journal of Dermatology”

In this report, six elderly women with a novel pustular dermatosis of the scalp experienced chronic lesions unresponsive to antibiotics but were effectively managed with potent topical steroids.

research Hot Comb Alopecia

107 citations , September 1968 in “Archives of Dermatology”

In this study, researchers identified a form of irreversible scalp alopecia in Black women using hot combs, characterized by incomplete hair loss primarily on the crown and follicular scarring.