Central Centrifugal Cicatricial Alopecia: Challenges and Solutions

August 2016 in “ Clinical, Cosmetic and Investigational Dermatology ”

Ingrid Herskovitz, Mariya Miteva

Central Centrifugal Cicatricial Alopecia CCCA scarring alopecia dermoscopy topical steroids intralesional steroids calcineurin inhibitors minoxidil histopathological features Rogaine

TLDR The document concludes that better treatments for CCCA are needed and more research is required to understand its causes related to hairstyling and genetics.

The document from August 1, 2016, addresses Central Centrifugal Cicatricial Alopecia (CCCA), a scarring alopecia most common among African American women, with an unclear etiology but potential links to hairstyling practices and genetic factors. Dermoscopy is useful for diagnosis, and while there are no randomized controlled trials for treatment, recommendations include avoiding certain hair care practices and using topical and intralesional steroids, calcineurin inhibitors, and minoxidil to potentially halt progression. A retrospective study of 51 patients provided insight into histopathological features of CCCA. The document calls for more research to understand the influence of grooming techniques and genetics, and to develop effective treatments.

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