Dermatoscopic Features of Central Centrifugal Cicatricial Alopecia

June 2014 in “ Journal of The American Academy of Dermatology ”

Mariya Miteva, Antonella Tosti

central centrifugal cicatricial alopecia CCCA dermatoscopy peripilar white halo lamellar fibrosis broken hairs inflammation terminal to vellus hair ratio

Studysummary This study found that a peripilar white gray halo around hair emergence is a highly specific and sensitive dermatoscopic feature for diagnosing central centrifugal cicatricial alopecia in African American patients with mild central thinning.

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In 2014, researchers studied the dermatoscopic features of central centrifugal cicatricial alopecia (CCCA) in 51 African American women, using 153 nonpolarized dermatoscopic images. They identified a peripilar white halo around hair emergence in 94% of patients, which was specific and sensitive for diagnosing CCCA. This feature corresponds to lamellar fibrosis on pathology. The study also observed broken hairs in 24% of cases, indicating inflammation and a diagnostic feature of CCCA. Additionally, the alopecic area had a lower terminal to vellus hair ratio than normal. These findings are intended to assist in early detection and treatment of CCCA.

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research Hair Breakage as a Presenting Sign of Early or Occult Central Centrifugal Cicatricial Alopecia

44 citations , September 2012 in “Archives of Dermatology”

This study observed that hair breakage may indicate early central centrifugal cicatricial alopecia in African American women, suggesting that it should be considered in their differential diagnosis.

research Hair and Scalp Dermatoscopy

245 citations , March 2012 in “Journal of The American Academy of Dermatology”

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research Prevalence and Etiology of Central Centrifugal Cicatricial Alopecia

19 citations , August 2011 in “Archives of Dermatology”

This abstract contains no research findings but is a snippet of a website interface for JAMA Dermatology.

Reflectance Confocal Microscopy Can Differentiate Dermoscopic White Dots of the Scalp Between Sweat Gland Ducts or Follicular Infundibulum

research Reflectance Confocal Microscopy Can Differentiate Dermoscopic White Dots of the Scalp Between Sweat Gland Ducts or Follicular Infundibulum

20 citations , April 2011 in “British Journal of Dermatology”

Reflectance confocal microscopy can tell apart white dots on the scalp as either sweat gland ducts or hair follicle openings.

research Medical and Environmental Risk Factors for the Development of Central Centrifugal Cicatricial Alopecia

88 citations , April 2011 in “Archives of Dermatology”

This study found a high prevalence of central hair loss among African American women and associated it with diabetes mellitus type 2, bacterial scalp infections, and hairstyles causing traction.

research Corkscrew Hair: A New Dermoscopic Sign for Diagnosis of Tinea Capitis in Black Children

108 citations , March 2011 in “Archives of Dermatology”

Corkscrew hair may be a new sign for quickly diagnosing scalp fungus in black children.

research Central Hair Loss in African American Women: Incidence and Potential Risk Factors

76 citations , November 2010 in “Journal of The American Academy of Dermatology”

In this study, a photographic scale and questionnaire revealed that extensive central scalp hair loss was observed in 5.6% of African American women, with an association to a history of tinea capitis.

research Pinpoint White Dots in the Scalp: Dermoscopic and Histopathologic Correlation

60 citations , September 2010 in “Journal of the American Academy of Dermatology”

Small white dots on the scalp seen with a dermoscope correspond to sweat ducts and vary with different hair disorders.

research Dermoscopy Findings of Alopecia Areata in an African-American Patient

25 citations , December 2008 in “Journal of Dermatological Case Reports”

This case report describes alopecia areata dermoscopy in an African-American patient, revealing novel patterns such as a diffuse honeycomb-like pigmented network and white dots, suggesting skin color may affect dermoscopic findings.

research Central Scalp Alopecia Photographic Scale in African American Women

46 citations , July 2008 in “Dermatologic Therapy”

This study developed and evaluated a photographic scale to assess CCCA pattern and severity in African American women, finding it reproducible when used by investigators and participants.

research Female Pattern Hair Loss and Its Relationship to Permanent/Cicatricial Alopecia: A New Perspective

73 citations , November 2005 in “Journal of Investigative Dermatology Symposium Proceedings”

This article reviews the potential relationship between different forms of permanent hair loss such as cicatricial pattern hair loss and discusses related conditions, reporting no new clinical findings.

research Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia

309 citations , May 1993 in “Journal of The American Academy of Dermatology”

This study concluded that horizontal sections of scalp biopsy specimens provide more diagnostic information for male pattern androgenetic alopecia than vertical sections and can predict hair regrowth potential following topical minoxidil therapy.

research Hot Comb Alopecia

107 citations , September 1968 in “Archives of Dermatology”

In this study, researchers identified a form of irreversible scalp alopecia in Black women using hot combs, characterized by incomplete hair loss primarily on the crown and follicular scarring.