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GlossaryCentral Centrifugal Cicatricial Alopecia (CCCA)

scarring hair loss starting at the scalp's crown, common in African American women

Central Centrifugal Cicatricial Alopecia (CCCA) is a type of scarring hair loss that typically starts at the crown of the scalp and spreads outward in a circular pattern. It is most commonly seen in African American women and can lead to permanent hair loss due to the destruction of hair follicles and subsequent scarring.

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research Support for Dermatological Research in Sub-Saharan Africa: Insights from African Hair and Skin Research Programs

February 2024 in “International Journal of Dermatology”

The document concludes that more local research on African skin and hair is needed despite increased scientific output from Sub-Saharan Africa.

research Use of Platelet-Rich Plasma in Cicatricial Alopecia

28 citations , August 2018 in “Dermatologic Surgery”

Platelet-Rich Plasma (PRP) may help improve hair density in primary cicatricial alopecias (PCAs) patients, but more trials are needed to confirm its benefits.

research Fibrosing Alopecia in a Pattern Distribution

1 citations , July 2018 in “Elsevier eBooks”

FAPD and possibly CCCA may be AGA subtypes, and treatments combining antiandrogens, hair growth agents, hair transplants, and anti-inflammatories could be effective.

research Central Centrifugal Cicatricial Alopecia: New Insights and a Call for Action

27 citations , September 2017 in “Journal of Investigative Dermatology Symposium Proceedings”

Hair loss in black women needs more research, early intervention, and community education.

research Pili Trianguli Et Canaliculati as a Phenotypic Subtype in Patients with Central Centrifugal Cicatricial Alopecia: A Scanning Electron Microscopy Study

2 citations , May 2020 in “Journal of the American Academy of Dermatology”

Hair shaft changes may be linked to CCCA, but their role is unclear.

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community Starting Treatment for CCCA (scarring alopecia)

in Treatment 6 upvotes 2 years ago

A male in his early 20s with CCCA (scarring alopecia) started treatment with Finasteride, Fluocinolone, and Doxycycline. Steroid injections were suggested but not yet done.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 3 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community scarring alopecia awareness in this community

in Chat 33 upvotes 3 years ago

Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

community Wanted to say that Derma rolling and Pumpkin seed oil helped my crown out.

in Treatment 4 upvotes 6 years ago

Derma rolling, pumpkin seed oil, and daily massages helped regrow weak hairs on the crown. Nizoral shampoo and yoga also contributed to reducing scalp pain and stress.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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