The Spectrum of Fibrosing Alopecias

    July 2022 in “ JEADV Clinical Practice
    Gloria Orlando, Bianca Maria Piraccini, Michela Starace
    Image of study
    TLDR The document concludes that different types of permanent hair loss conditions are related and early treatment is key to preventing further damage.
    The document discusses cicatricial alopecia, a group of disorders causing permanent hair loss due to hair follicles being replaced by scar tissue. It focuses on four subtypes: Classical Lichen Planopilaris (LPP), Frontal Fibrosing Alopecia (FFA), Fibrosing Alopecia in a Pattern Distribution (FAPD), and Lichen Planopilaris Diffuse Pattern (LPPDP). These conditions share similar trichoscopic and histologic features, suggesting they exist along a spectrum. Treatments vary depending on the subtype and severity of the condition. The document also discusses Central Centrifugal Cicatricial Alopecia (CCCA) and LPP Diffuse Pattern, which primarily affects African Americans and is suggested to be triggered by certain hair products. Treatments aim to halt disease progression, with early treatment being crucial to potentially rescue early-damaged follicles.
    Discuss this study in the Community →

    Research cited in this study

    49 / 49 results

    Related Community Posts Join

    6 / 13 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Comprehensive Microneedling Guide

      in Microneedling  295 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Finasteride not working isnt it MPB?

      in Finasteride/Dutasteride  5 upvotes 6 months ago
      A user is concerned that finasteride isn't working for their hair loss, questioning if it's due to male pattern baldness or low iron levels. They are advised to take finasteride daily and get blood work done.

    Related Research

    5 / 5 results