Cicatricial Alopecia: Overview and Treatment Recommendations

April 2018 in “ Journal der Deutschen Dermatologischen Gesellschaft ”

Varvara Kanti, Joachim Röwert-Huber, Annika Vogt, Ulrike Blume-Peytavi

cicatricial alopecia primary cicatricial alopecias PCAs permanent hair loss scalp scarring trichoscopy scalp biopsies topical corticosteroids intralesional triamcinolone acetonide DLE LPP FFA inflammation off-label treatments scarring alopecia triamcinolone discoid lupus erythematosus lichen planopilaris frontal fibrosing alopecia

Studysummary This review discusses the classification and diagnosis of primary cicatricial alopecias and reports no new clinical results; it highlights the need for effective treatments owing to limited evidence of current therapies' efficacy.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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Research cited in this study

11 / 11 results

research Frontal Fibrosing Alopecia: Clinical and Prognostic Classification

74 citations , April 2017 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

This study classified frontal fibrosing alopecia patients into three clinical patterns, finding that pattern III had the best prognosis and pattern II the worst after treatment with dutasteride and corticosteroids.

research Primary Cicatricial Alopecia

65 citations , November 2016 in “Journal of The American Academy of Dermatology”

This article reviews various types of primary cicatricial alopecias and emphasizes the importance of accurate diagnosis to improve management strategies, particularly detailing remaining lymphocytic forms and expanding on neutrophilic and mixed types.

research Primary Cicatricial Alopecia: Treatment Approaches and Classification

95 citations , November 2016 in “Journal of The American Academy of Dermatology”

This article reviews primary cicatricial alopecias, focusing on lymphocytic forms such as chronic cutaneous lupus erythematosus, according to a classification by the North American Hair Research Society, and reports no new clinical results.

research Special Stains and Immunohistochemical Stains in Hair Pathology

11 citations , April 2016 in “The American Journal of Dermatopathology”

This review discusses the current knowledge on using special and immunohistochemical stains for diagnosing hair disorders, concluding that no stains are recommended for routine use in hair pathology.

research Frontal Fibrosing Alopecia Treatment Options

20 citations , January 2016 in “Intractable & Rare Diseases Research”

In this clinical experience, treating frontal fibrosing alopecia with oral finasteride, hydroxychloroquine, tacrolimus, and excimer laser was associated with optimal results in patients with active inflammation.

research Finasteride-Mediated Hair Regrowth and Reversal of Atrophy in a Patient with Frontal Fibrosing Alopecia

24 citations , September 2015 in “JAAD case reports”

This case report describes a patient with frontal fibrosing alopecia experiencing significant hair regrowth and reversal of cutaneous atrophy after treatment with the 5α-reductase inhibitor finasteride.

research Primary Cicatricial Alopecia: Diagnosis and Treatment

48 citations , May 2013 in “Canadian Medical Association Journal”

This article discusses common causes of hair loss, specifically androgenetic alopecia and alopecia areata, but reports no new clinical findings.

research Frontal Fibrosing Alopecia: A Review of 60 Cases

166 citations , April 2012 in “Journal of The American Academy of Dermatology”

This study reviewed clinical data from 60 patients with frontal fibrosing alopecia and found increasing prevalence and generally poor response to treatment, with the cause remaining unclear.

research Diagnosis of Hair Disorders

73 citations , March 2009 in “Seminars in Cutaneous Medicine and Surgery”

This article reviews various diagnostic tools for hair disorders, describing methods ranging from invasive to noninvasive, but reports no new research findings or clinical results.

research Frontal Fibrosing Alopecia: Treatment with Oral Dutasteride and Topical Pimecrolimus

69 citations , August 2008 in “Journal of The European Academy of Dermatology and Venereology”

Oral dutasteride and topical pimecrolimus can safely and effectively treat Frontal Fibrosing Alopecia, leading to significant hair regrowth.

research Management of Primary Cicatricial Alopecias: Options for Treatment

98 citations , May 2008 in “British Journal of Dermatology”

This review discusses evidence-based guidance for managing primary cicatricial alopecias but reports no new clinical results, highlighting significant gaps in knowledge and the need for more quality trials.