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GlossaryDiscoid Lupus Erythematosus (DLE)

chronic autoimmune condition causing red, scaly skin patches

Discoid Lupus Erythematosus (DLE) is a chronic autoimmune condition that primarily affects the skin, leading to the development of red, inflamed, and scaly patches, often on the face, scalp, and ears. These lesions can cause scarring and permanent hair loss if they occur on the scalp.

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research Dramatic Response of Scarring Scalp Discoid Lupus Erythematosus to Intravenous Methylprednisolone, Oral Corticosteroids, and Hydroxychloroquine in a 5-Year-Old Child

19 citations, May 2009 in “Pediatric Dermatology”

A 5-year-old girl's scalp scarring and hair loss from lupus improved with specific medications.

Reply to: Severe Diffuse Non-Scarring Hair Loss in Systemic Lupus Erythematosus - Clinical and Histopathological Analysis of Four Cases

research Reply to: Severe Diffuse Non-Scarring Hair Loss in Systemic Lupus Erythematosus - Clinical and Histopathological Analysis of Four Cases

3 citations, January 2013 in “Journal of the European Academy of Dermatology and Venereology”

The document suggests that severe hair loss in SLE patients may be an early sign of scalp DLE, treatable with immunosuppressive therapy.

research Concentrated Growth Factor Therapy as Cosmetic Treatment in Discoid Lupus Erythematosus

February 2024 in “Journal of dermatology”

CGF therapy may help hair regrowth and improve scars in DLE patients.

research Histopathologic Evaluation of Alopecias

90 citations, June 2006 in “The American Journal of Dermatopathology”

The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.

research Dermoscopic Pattern of Cicatricial Alopecia Caused by Discoid Lupus Erythematosus and Lichen Planopilaris

73 citations, April 2010 in “Anais Brasileiros de Dermatologia”

Dermoscopy helps diagnose and monitor treatment for hair loss from scarring conditions like discoid lupus and lichen planopilaris.

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community Progress after about a year (13 months min 9 months fin and keto shampoo)

in Progress Pictures 113 upvotes 1 year ago

User experienced regrowth and thicker hair after using Minoxidil, Finasteride, and Keto shampoo for about a year. They also mentioned using 5% topical Minoxidil, 1mg oral Finasteride, and vitamin D.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 2 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.