Clinical Description of Frontal Fibrosing Alopecia with Concomitant Lichen Planopilaris

September 2017 in “ Skin appendage disorders ”

David Saceda‐Corralo, Pablo Fernández‐Crehuet, Pablo Fonda‐Pascual, Cristina Pindado‐Ortega, Óscar M. Moreno‐Arrones, Sergio Vañó‐Galván

Frontal Fibrosing Alopecia Lichen Planopilaris pruritus lichenoid reactions non-scalp hair involvement FFA LPP itching

TLDR Some women with Frontal Fibrosing Alopecia also have Lichen Planopilaris, which can lead to more symptoms and affect hair outside the scalp.

The study analyzed 103 female patients with Frontal Fibrosing Alopecia (FFA), finding that 17 (16.5%) also had Lichen Planopilaris (LPP). The average age of these patients was 67.9 years, with the onset of FFA or LPP at an average age of 63.9 years. It was observed that those with both conditions experienced more frequent involvement of non-scalp hair areas and symptoms such as pruritus and pain, indicating a greater likelihood of intense lichenoid reactions. The research highlighted the potential for misdiagnosis when FFA and LPP coexist and suggested that symptoms and non-scalp hair involvement could be more common in patients with both conditions.

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research Lichen Planopilaris Epidemiology: A Retrospective Study of 80 Cases

37 citations , October 2015 in “Anais Brasileiros de Dermatologia”

Lichen planopilaris mostly affects women with fair skin and can look different on each person, needing early treatment to prevent hair loss.

research Frontal Fibrosing Alopecia and Lichen Planopilaris in HLA-Identical Mother and Daughter

12 citations , January 2015 in “Indian Journal of Dermatology, Venereology and Leprology”

A mother and daughter with similar hair loss conditions and identical HLA types suggest a genetic link between the conditions.

research Frontal Fibrosing Alopecia: A Retrospective Clinical Review of 62 Patients with Treatment Outcome and Long-Term Follow-Up

102 citations , April 2014 in “International Journal of Dermatology”

The treatment helped reduce symptoms and stabilize the hairline in most patients with Frontal Fibrosing Alopecia, but hair regrowth was limited.

research Frontal Fibrosing Alopecia: A Multicenter Review of 355 Patients

339 citations , April 2014 in “Journal of The American Academy of Dermatology”

Most patients with frontal fibrosing alopecia are postmenopausal women, and treatments like finasteride and dutasteride can improve or stabilize the condition.

research Frontal Fibrosing Alopecia: A Retrospective Review of 19 Patients Seen at Duke University

98 citations , May 2013 in “Journal of The American Academy of Dermatology”

Dutasteride may help stabilize Frontal Fibrosing Alopecia, but more research is needed.

research Frontal Fibrosing Alopecia: A Review of 60 Cases

166 citations , November 2012 in “Journal of The American Academy of Dermatology”

Mostly postmenopausal Caucasian women get Frontal Fibrosing Alopecia, which often includes eyebrow loss and has limited treatment success.

research Postmenopausal Frontal Fibrosing Alopecia: A Frontal Variant of Lichen Planopilaris

329 citations , January 1997 in “Journal of the American Academy of Dermatology”

Frontal fibrosing alopecia is a hair loss condition in postmenopausal women, similar to lichen planopilaris, with ineffective treatments.