Scalp Itch: A Systematic Review

    November 2017 in “ Skin appendage disorders
    Norma Elizabeth Vázquez-Herrera, Divya Sharma, Nouf Mohammed Aleid, Antonella Tosti
    Image of study
    TLDR The document concludes that accurate diagnosis and treatment of scalp itch require differentiating between various conditions using a proposed five-step evaluation process.
    The 2017 document reviewed scalp itch and proposed a classification system based on the presence of dermatological lesions and hair loss. It introduced the SCALLP acronym for common causes: seborrheic dermatitis, contact dermatitis, anxiety, lichen planopilaris, lice, and psoriasis. The review recommended a five-step evaluation process and discussed the pathophysiology, including the role of neuromediators, scalp sebum, and microflora. It noted that seborrheic dermatitis affects about 16% of adults, and psoriasis has an itch prevalence of 67-97%. Contact dermatitis is often related to hair product allergens. The review also covered less common causes and diagnostic tools like trichoscopy. Additionally, it detailed conditions associated with scalp itch, such as sensitive scalp (60% of patients), atopic dermatitis (49.7% with scalp involvement), non-scarring alopecias (alopecia areata, androgenetic alopecia), scarring alopecias (LPP, frontal fibrosing alopecia, discoid lupus erythematosus, central centrifugal cicatricial alopecia), urticarial lesions, infestations, and systemic diseases (dermatomyositis, systemic lupus erythematosus, scleroderma, Sjögren syndrome). Accurate diagnosis and treatment depend on differentiating between these conditions.
    Discuss this study in the Community →

    Research cited in this study

    24 / 24 results

    Related Community Posts Join

    6 / 552 results

      community I tried salt water to stop the DHT itch

      in Treatment  58 upvotes 3 years ago
      Treating the itch associated with male pattern baldness, which is believed to be caused by DHT. Potential treatments discussed include salt water, finasteride, ketoconazole, and RU58841.

      community 9 months on Fin - no progress , should I get on Dutasteride?

      in Chat  10 upvotes 1 year ago
      The user has been using finasteride, minoxidil, and nizoral for hair loss but hasn't seen regrowth, only maintenance. They are considering switching to dutasteride, which is believed to be more effective, but are concerned about potential side effects.

      community Is anyone else allergic to Minoxidil

      in Minoxidil  4 upvotes 1 year ago
      A user experienced a painful rash from both liquid and foam minoxidil, suggesting an allergy to minoxidil itself. They are seeking others with similar experiences.

      community Effects of 2% vs 5% min for sebderm

      in Minoxidil  1 upvotes 1 year ago
      Switching from 2% liquid minoxidil to 5% foam minoxidil reduced scalp irritation but increased eyebrow flakiness and thinning. The user speculates that propylene glycol in the liquid formulation might have been protecting against seborrheic dermatitis while causing contact dermatitis.

      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  445 upvotes 3 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

    Similar Research

    5 / 1000+ results