Recent Advances in Understanding of the Etiopathogenesis, Diagnosis, and Management of Hair Loss Diseases

    May 2023 in “ Journal of Clinical Medicine
    Misaki Kinoshita‐Ise, Masafumi Fukuyama, Manabu Ohyama
    Image of study
    TLDR New understanding and treatments for hair loss are improving, but more research is needed.
    The document reviews recent advances in understanding the causes, diagnosis, and management of hair loss diseases. It emphasizes the importance of accurate diagnosis and disease severity assessment for effective treatment. New diagnostic systems and techniques, such as trichoscopy and hair pull tests, are discussed. The paper also highlights breakthroughs in hair follicle biology and immunology, which have led to a deeper understanding of hair loss diseases. It discusses the genetic and epidemiological analysis that has elucidated disease susceptibility for androgenetic alopecia (AGA) and female pattern hair loss (FPHL). The association between COVID-19 and hair loss, with telogen effluvium being the predominant pathomechanism, is also mentioned. The document reviews several treatment options, including oral 5-α reductase inhibitors, finasteride and dutasteride, minoxidil, Platelet-Rich Plasma (PRP) treatment, hormone-modulating therapies, hair transplantation, low-level laser therapy (LLLT), topical cetirizine, and autologous-cell-based therapy. The document concludes by stating that more research is needed to fully establish these and other treatments as therapeutic options for hair loss diseases.
    Discuss this study in the Community →

    Research cited in this study

    100 / 100 results

    Related Community Posts Join

    6 / 40 results

      community Is anyone using melatonin for hair loss?

      in Research/Science  9 upvotes 6 months ago
      Melatonin is being discussed as a potential treatment for hair loss, with questions about its effectiveness and whether it should be used topically or orally. No specific conclusions or personal experiences were shared.

      community 1 month Pyrilutamide. A non responders story to everything.

      in Research/Science  218 upvotes 2 years ago
      My hairline, I am only 23. This conversation is about a user's experience with treatments for androgenic alopecia, including finasteride, dutasteride, RU, minoxidil, progesterone, melatonin, LLLT, oral minoxidil, and Pyrilutamide. They have tried many treatments over the course of two years without seeing much success, and they are considering getting a hair system as a last resort.

      community Follow up appointment with Donovan.

      in Finasteride/Dutasteride  17 upvotes 1 year ago
      The user was diagnosed with DUPA and initially treated with finasteride, then switched to dutasteride which worsened their hair loss. They are now returning to finasteride and adding treatments including oral minoxidil, Proscar, Viviscal, pumpkin seed oil, LLLT, and Nizoral shampoo, hoping for hair regrowth.

      community Here's why you don't assume you have TE, because you likely don't

      in Chat  49 upvotes 3 months ago
      TE (telogen effluvium) is often misunderstood and is triggered by severe stress or trauma, not minor daily inconveniences. Most hair loss cases are due to male pattern baldness (AGA), and treatments like Minoxidil and finasteride can help.

      community I think I’ve finally found the reason for my hair loss

      in Chat  98 upvotes 2 weeks ago
      The user experienced hair loss since 2019 and tried finasteride, dutasteride, RU58841, and ketoconazole shampoo without success. A scalp biopsy showed scarring and inflammation from folliculitis, indicating chronic inflammation was affecting treatment effectiveness.

    Related Research

    3 / 3 results