A Comparative Study of Therapeutic Response to Intralesional Injections of Platelet-Rich Plasma Versus Triamcinolone Acetonide in Alopecia Areata

    January 2020 in “ Indian Dermatology Online Journal
    Anumod Balakrishnan, Bifi Joy, Anoop Thyvalappil, Pretty Mathew, Ajayakumar Sreenivasan, Rajiv Sridharan
    TLDR PRP works faster and is a safe alternative to steroids for treating alopecia areata.
    This study compared the effectiveness of intralesional platelet-rich plasma (PRP) versus triamcinolone acetonide in treating alopecia areata over 12 weeks with 40 patients, 16 completing the study in each group. Both treatments showed similar outcomes, but PRP demonstrated a statistically significant earlier response at 8 weeks and had a higher percentage of patients reporting excellent and good responses. Side effects were minimal, with severe pain reported by 3 patients in the PRP group. PRP was found to be a safe and effective alternative to steroids, though the study's small sample size and short follow-up duration necessitated further research.
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