A Comparative Study of Therapeutic Response to Intralesional Injections of Platelet-Rich Plasma Versus Triamcinolone Acetonide in Alopecia Areata

January 2020 in “ Indian Dermatology Online Journal ”

Anumod Balakrishnan, Bifi Joy, Anoop Thyvalappil, Pretty Mathew, Ajayakumar Sreenivasan, Rajiv Sridharan

platelet-rich plasma triamcinolone acetonide alopecia areata intralesional injections steroids PRP

From the encyclopedia

Platelet-Rich Plasma →

growth factors taken from your blood and injected into your scalp to stimulate hair

Triamcinolone Acetonide →

Alopecia Areata →

autoimmune disorder causing patchy hair loss

Studysummary In this study, PRP injections showed comparable effectiveness to triamcinolone for alopecia areata, with a significant decrease in SALT score at one interval, and 12.5% of patients in the PRP group experienced excellent hair regrowth compared to none in the triamcinolone group.

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research The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation

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This study reported that AA-PRP injections significantly increased hair count and density in individuals with pattern hair loss compared to baseline, demonstrating their potential for enhancing hair growth.

research Platelet-Rich Plasma in Androgenic Alopecia: Myth or Effective Tool

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In this study, PRP injections increased hair count and reduced hair loss in patients with androgenic alopecia not responding to minoxidil and finasteride, with high patient satisfaction reported.

A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

research A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

205 citations , April 2013 in “British Journal of Dermatology”

In this study, platelet-rich plasma significantly increased hair regrowth and reduced symptoms of alopecia areata compared to triamcinolone acetonide or placebo, with no observed side effects.

research Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

270 citations , March 2012 in “Dermatologic Surgery”

This study found that autologous platelet-rich plasma increased hair growth potential by enhancing dermal papilla cell proliferation and stimulating key signaling pathways in both cell cultures and mice models.

research Pitx2, A β-Catenin-Regulated Transcription Factor, Regulates The Differentiation Of Outer Root Sheath Cells Cultured In Vitro

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research Intralesional Treatment of Alopecia Areata with Triamcinolone Acetonide by Jet Injector

100 citations , July 2006 in “British Journal of Dermatology”

This study found that intralesional triamcinolone acetonide injections using a needleless injector led to rapid hair regrowth in patients with limited alopecia areata, while lasting growth was rare in alopecia totalis.

research Management of Hair Loss

74 citations , April 2005 in “Dermatologic Clinics”

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research A Comparison of Intralesional Triamcinolone Hexacetonide and Triamcinolone Acetonide in Alopecia Areata

75 citations , September 1971 in “British Journal of Dermatology”

This study found that both intralesional triamcinolone acetonide and triamcinolone hexacetonide promote continuous hair growth in alopecia areata, with effects lasting at least 9 months after a single injection.