Permanent Hair Loss in a Patient with Hypersensitivity to Intralesional Triamcinolone Injection

    Young In Lee, Minseok Lee, Sewon Lee, Doyoung Kim
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    Mesotherapy →

    technique to inject very small amounts of beneficial chemicals into the scalp

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    Studysummary This case report highlights a rare instance of permanent hair loss caused by an allergic reaction to a mesotherapy mixture containing triamcinolone acetonide, suggesting that hypersensitivity reactions to such mixtures are possible. Our plain-language summary of this paper — not a Tressless recommendation.
    This case report described a rare instance of permanent hair loss in a patient due to an allergic reaction to a mesotherapy mixture containing triamcinolone acetonide. The patient was diagnosed with scarring alopecia caused by a delayed type IV hypersensitivity reaction to the corticosteroid, confirmed by a positive intradermal allergic skin test. The study highlighted the importance for dermatologists to be aware of both IgE-mediated and non-IgE-mediated hypersensitivity reactions to corticosteroids and mesotherapy excipients to prevent irreversible adverse events.
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