Delayed Hypersensitivity Reaction to Intralesional Triamcinolone Acetonide Following Treatment for Alopecia Areata: Intradermal Testing

    Firas Constantin Kreeshan, P. Hampton
    TLDR Intradermal testing can better detect corticosteroid allergies than patch testing.
    The document described a case of a 35-year-old woman who developed a delayed hypersensitivity reaction to intralesional triamcinolone acetonide after treatment for alopecia areata. Patch testing was negative for triamcinolone but positive for budesonide, indicating a corticosteroid allergy. Intradermal testing with triamcinolone elicited a strong positive reaction, confirming the allergy. The study concluded that while patch testing is generally effective for detecting corticosteroid allergies, it may fail in some cases, and intradermal testing, though less safe, can be a more sensitive diagnostic tool.
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