Drug Repurposing in Dermatology: Molecular Biology and Omics Approach

The document discusses the potential of drug repurposing in dermatology, particularly for conditions like alopecia, psoriasis, acne, hirsutism, and hyperpigmentation. It highlights the successful repositioning of drugs like finasteride for androgenic alopecia and spironolactone for polycystic ovary syndrome and hirsutism. The document also presents findings on the effects of various drugs on hair loss and growth. For instance, oral valproate can induce hair loss, while its topical application can promote hair growth. Other drugs like minoxidil, originally for hypertension, have been repurposed for hair regrowth in androgenic alopecia patients. The document also mentions other drugs like Bimatoprost, Phenytoin, Bevacizumab, Tofacitinib, Metformin, Niclosamide, Beta-blockers, and Cannabidiol, which have potential for new applications in dermatology.