Minoxidil Promotes Hair Growth Through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells

February 2018 in “ International Journal of Molecular Sciences ”

Nahyun Choi, Soyoung Shin, Sun Ok Song, Jong Hwan Sung

minoxidil growth factors adipose-derived stem cells hair growth cycle cell migration Rogaine

TLDR Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.

A study from 2018 found that minoxidil promotes hair growth by stimulating the release of growth factors from adipose-derived stem cells. This can potentially lead to new hair growth treatments. Minoxidil was found to promote hair growth in mice and ex vivo organ culture by stimulating the release of growth factors from stem cells, which speeds up the hair growth cycle. The drug does not affect cell proliferation but increases cell migration in a dose-dependent manner. The effect is specific to adipose-derived stem cells, suggesting that minoxidil directly promotes hair growth by stimulating these cells.

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17 / 17 results

research Hair Follicle Growth by Stromal Vascular Fraction-Enhanced Adipose Transplantation in Baldness

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$Isolation of Adipose-Derived Stem Cells Using a Subfractionation Culturing Method$

research Isolation of Adipose-Derived Stem Cells Using a Subfractionation Culturing Method

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research Hair Growth Effect of Minoxidil

25 citations , March 2002 in “Folia Pharmacologica Japonica”

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research Minoxidil-Induced Hair Growth Is Mediated by Adenosine in Cultured Dermal Papilla Cells: Possible Involvement of Sulfonylurea Receptor 2B as a Target of Minoxidil

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3 / 3 results

Minoxidil Promotes Hair Growth Through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells

Cited in this study

research Hair Follicle Growth by Stromal Vascular Fraction-Enhanced Adipose Transplantation in Baldness

research LL-37 Stimulates the Functions of Adipose-Derived Stromal/Stem Cells via Early Growth Response 1 and the MAPK Pathway

research Megestrol Acetate Increases the Proliferation, Migration, and Adipogenic Differentiation of Adipose-Derived Stem Cells via Glucocorticoid Receptor

research Isolation of Adipose-Derived Stem Cells Using a Subfractionation Culturing Method

research The Molecular Mechanism Underlying the Proliferating and Preconditioning Effect of Vitamin C on Adipose-Derived Stem Cells

research Minoxidil May Suppress Androgen Receptor-Related Functions

research Ultraviolet B Preconditioning Enhances the Hair Growth-Promoting Effects of Adipose-Derived Stem Cells Via Generation of Reactive Oxygen Species

research Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling

research Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect

research Hair Growth Promoting Effects of Adipose Tissue-Derived Stem Cells

research Promotive Effect of Minoxidil Combined with All-Trans Retinoic Acid (Tretinoin) on Human Hair Growth In Vitro

research Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle

research Hair Growth Effect of Minoxidil

research Minoxidil-Induced Hair Growth Is Mediated by Adenosine in Cultured Dermal Papilla Cells: Possible Involvement of Sulfonylurea Receptor 2B as a Target of Minoxidil

research Activation of Cytoprotective Prostaglandin Synthase-1 by Minoxidil as a Possible Explanation for Its Hair Growth-Stimulating Effect

research Minoxidil Stimulates Mouse Vibrissae Follicles in Organ Culture

research Hair Follicle Biology and Topical Minoxidil: Possible Mechanisms of Action

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