Minoxidil Promotes Hair Growth Through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells

    Nahyun Choi, Soyoung Shin, Sun Ok Song, Jong Hwan Sung
    Studysummary This study suggests that minoxidil may enhance hair growth by stimulating adipose-derived stem cell motility and growth factor secretion, promoting dermal papilla cell proliferation and accelerating anagen induction.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 20

    1. Hair Follicle Growth by Stromal Vascular Fraction-Enhanced Adipose Transplantation in Baldness Stem cells and cloning · 2017
    2. LL-37 Stimulates the Functions of Adipose-Derived Stromal/Stem Cells via Early Growth Response 1 and the MAPK Pathway Stem cell research & therapy · 2016
    3. Hair Regeneration Using Adipose-Derived Stem Cells PubMed · 2016
    4. Megestrol Acetate Increases the Proliferation, Migration, and Adipogenic Differentiation of Adipose-Derived Stem Cells via Glucocorticoid Receptor Stem Cells Translational Medicine · 2015
    5. Functional Regulation of Adipose-Derived Stem Cells by PDGF-D Stem Cells · 2014
    6. Isolation of Adipose-Derived Stem Cells Using a Subfractionation Culturing Method Expert Opinion on Biological Therapy · 2014
    7. Minoxidil May Suppress Androgen Receptor-Related Functions Oncotarget · 2014
    8. The Molecular Mechanism Underlying the Proliferating and Preconditioning Effect of Vitamin C on Adipose-Derived Stem Cells Stem Cells and Development · 2014
    9. Ultraviolet B Preconditioning Enhances the Hair Growth-Promoting Effects of Adipose-Derived Stem Cells Via Generation of Reactive Oxygen Species Stem Cells and Development · 2012
    10. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011
    11. Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect Journal of Dermatological Science · 2011
    12. Hair Growth Promoting Effects of Adipose Tissue-Derived Stem Cells Journal of Dermatological Science · 2009
    13. Hair Follicle Biology and Topical Minoxidil: Possible Mechanisms of Action Dermatology · 2009
    14. Promotive Effect of Minoxidil Combined with All-Trans Retinoic Acid (Tretinoin) on Human Hair Growth In Vitro Journal of Korean Medical Science · 2007
    15. PDGF Isoforms Induce and Maintain Anagen Phase of Murine Hair Follicles Journal of Dermatological Science · 2006
    16. Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle Journal of Dermatological Science · 2004
    17. Hair Growth Effect of Minoxidil Folia Pharmacologica Japonica · 2002
    18. Minoxidil-Induced Hair Growth Is Mediated by Adenosine in Cultured Dermal Papilla Cells: Possible Involvement of Sulfonylurea Receptor 2B as a Target of Minoxidil Journal of Investigative Dermatology · 2001
    19. Activation of Cytoprotective Prostaglandin Synthase-1 by Minoxidil as a Possible Explanation for Its Hair Growth-Stimulating Effect Journal of Investigative Dermatology · 1997
    20. Minoxidil Stimulates Mouse Vibrissae Follicles in Organ Culture Journal of Investigative Dermatology · 1989

    Related research 3

    1. Minoxidil Promotes Hair Growth Through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells International Journal of Molecular Sciences · 2018
    2. Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells British Journal of Dermatology · 1998
    3. Growth Factors in Hair Organ Development and the Hair Growth Cycle Dermatologic Clinics · 1996