Hair Growth Effect of Minoxidil

    January 2002 in “ Folia Pharmacologica Japonica ”
    Susumu Otomo
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    TLDR Minoxidil helps hair grow by improving blood flow and increasing growth factors in hair follicles.
    The 2002 document outlines the hair growth effects of minoxidil, a drug initially used for high blood pressure that was found to stimulate hair growth. Minoxidil is thought to work by activating the sulfonylurea receptor (SUR), which leads to increased blood flow, promotion of growth factors like VEGF, and prevention of cell death in hair follicles, thereby extending their growth phase. Although the exact mechanisms are not fully understood, minoxidil is believed to enhance cell growth factors, inhibit apoptosis, and improve blood flow, which together stimulate hair follicles. Minoxidil was FDA-approved in 1988 and is available in various concentrations, including 1% and 5% topical formulations.
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      community Being Safe on Oral Minoxidil: tl;dr on the literature.

      in Research/Science  49 upvotes 8 months ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

      community Switch from topical to oral minoxidil

      in Minoxidil  1 upvotes 5 days ago
      The conversation discusses switching from topical to oral minoxidil, using oral minoxidil daily and topical minoxidil only on microneedling days. The user also mentions using finasteride and tretinoin but has not seen results after two months.

      community After stopping the fall, take a more powerful minoxidil?

      in Minoxidil  1 upvotes 5 days ago
      The user has stopped hair loss using topical finasteride, dutasteride, minoxidil 5%, and a GHK-Cu melatonin caffeine blend. They are considering switching to a more potent minoxidil, specifically Dualgen 15%, for better regrowth results.

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